DEAE Dextran

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DEAE Dextran is a cationic derivative of dextran cationic (positively charged) in which diethylaminoethyl groups are attached to the dextran backbone (typically via chloride salt o f the tertiary amine). The DEAE-Dextran is based on 750,000 Da dextran biopolymer. It appears as a white to light tan powder and is highly water soluble. By introducing positively charged DEAE groups, the neutral dextran is transformed into a polycation. DEAE Dextran is historically significant as one of the first polymer-based transfection reagents and remains used for various biochemical applications requiring a polycationic polymer. Show more