DMG PEG2000 Alkyle – Catalog #B2013390 (25 mg) Catalog # B2013390 Lot # Batch dependent Expiration Batch dependent Amount 25 mg Molecular Weight / Conc. N/A Supplied As Solid Applications Molecular tool for various biochemical applications Storage –20 °C Keywords DMG-PEG2000-Alkyle; Alkyle PEG2000 DMG; 1,2-dimyristoyl-rac-glycero-3-polyethylene glycol 2000 alkyle Grade Biotechnology grade; highly pure; prepared with Type I ultrapure water (>18 MΩ·cm) and filtered through 0.22 µm DMG PEG2000 Alkyle is a specialized PEGylated lipid conjugate, merging dimyristoyl glycerol (DMG) with a 2000 Da polyethylene glycol (PEG) tail and an alkyl group—designed to enhance solubility, surface functionality, and formulation fidelity in liposomal and biochemical applications. Supplied as a solid (Catalog #B2013390, 25 mg), this versatile reagent enables lipid bilayer integration, surface steric stabilization, and customizable molecular architecture, making it an ideal molecular tool for applications across immunological, biochemical, and formulation disciplines. Produced under biotech-grade standards with rigorous purity and filtration, DMG PEG2000 Alkyle supports reproducible integration into liposome surfaces, functional micelle design, or biochemical tagging protocols. Its PEGylation enhances solubility and circulation time, facilitating development of stealth delivery vehicles, surface-modified probes, and scalable assay systems. Custom bulk quantities are available to support long-term or high-throughput studies—while storage at –20 °C ensures long-term reagent integrity. Why researchers choose this product: Combines lipid anchor (DMG), PEG shielding, and alkyl functionality for tunable molecular design Surface modification and solubility enhancement for liposomal and micellar formulations Biotech-grade purity ensures reproducibility in advanced biochemical workflows Compact, stable powder form allows for precise formulation Bulk availability supports project-scale implementation Indication for Use:This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or clinical use. References: 1: Liu D, Cohen J, Turkman N. PEG(2000)-DBCO surface coating increases intracellular uptake of liposomes by breast cancer xenografts. Sci Rep. 2022 Jun 22;12(1):10564. 2: Moghimi SM. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021 Mar 3;29(3):898-900. 3: Sponseller D, Blaisten-Barojas E. Solutions and Condensed Phases of PEG(2000) from All-Atom Molecular Dynamics. J Phys Chem B. 2021 Nov 25;125(46):12892-12901. 4: Carreño JM, Singh G, Tcheou J, Srivastava K, Gleason C, Muramatsu H, Desai P, Aberg JA, Miller RL, Study Group P, Pardi N, Simon V, Krammer F. mRNA-1273 but not BNT162b2 induces antibodies against polyethylene glycol (PEG) contained in mRNA-based vaccine formulations. Vaccine. 2022 Oct 6;40(42):6114-6124. 5: Smith MC, Crist RM, Clogston JD, McNeil SE. Zeta potential: a case study of cationic, anionic, and neutral liposomes. Anal Bioanal Chem. 2017 Sep;409(24):5779-5787. 6: Vieira J, Marcelino J, Ferreira F, Farinha S, Silva R, Proença M, Tomaz E. Skin testing with Pfizer SARS-CoV-2 vaccine and PEG 2000. Asia Pac Allergy. 2021 Apr 26;11(2):e18. 7: Klimek L, Novak N, Cabanillas B, Jutel M, Bousquet J, Akdis CA. Allergenic components of the mRNA-1273 vaccine for COVID-19: Possible involvement of polyethylene glycol and IgG-mediated complement activation. Allergy. 2021 Nov;76(11):3307-3313. 8: Zhang W, Wang Z, Wu C, Jin Y, Liu X, Wu Z, Liu J. The effect of DSPE-PEG(2000), cholesterol and drug incorporated in bilayer on the formation of discoidal micelles. Eur J Pharm Sci. 2018 Dec 1;125:74-85. 9: Tang L, Jiang W, Wu L, Yu X, He Z, Shan W, Fu L, Zhang Z, Zhao Y. TPGS2000-DOX Prodrug Micelles for Improving Breast Cancer Therapy. Int J Nanomedicine. 2021 Dec 1;16:7875-7890. 10: Yao Y, Ran G, Hou CL, Zhang R, Mangel DN, Yang ZS, Zhu M, Zhang W, Zhang JL, Sessler JL, Gao S, Zhang JL. Nonaromatic Organonickel(II) Phototheranostics. J Am Chem Soc. 2022 Apr 27;144(16):7346-7356.
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