Doctors Designs S-1000 Fatburner (90 Count) Thermoburner Nutrition Facts 45 Servings per ContainerServing Size 2 Capsules Directions 1. Take two (2) capsules one (1) to three (3) times a day, with 8 ozs (240ml) glass of water, 30 minutes before meals. Start with a low dose and build up to the most comfortable dosage level. 2. Do not exceed a dosage of 6 capsules per day.3. Do not exceed more than two (2) capsules at any one time.4. Wait 4 hours between doses.5. Not for sale to, or use by, persons under the age of 18. Keep out of the reach of children.6. Store at room temperature (59 degrees F - 86 degrees F).7. Keep in a dry place, Tightly closed.8. Avoid driving machinery until you know how this product affects you. WARNINGS: Seek advice from a healthcare practitioner prior to use if you are pregnant or nursing, have high blood pressure, heart or thyroid disease, diabetes, difficulty with urination due to prostate enlargement, or if you are taking prescription drugs. Do not use this product if you are taking appetite suppressants or products containing ephedrine or pseudoephedrine. Do not use if you are taking an MAO inhibitor or have taken a MAO inhibitor within 3 weeks. Reduce dose or discontinue use if nervousness, tremor, sleeplessness, severe loss of appetite,euphoria, nausea or constipation occur. Amount per Serving Total Calories 0 Fat 0gSaturated Fat 0gTrans Fat 0g Cholesterol 0mgSodium 0mg Total Carbohydrates 0gDietary Fiber 0gSugar 0gAdded Sugars 0g Protein 0g Ingredients * Proprietary Blend 952mgGreen Tea (leaf, extract)Citrus Aurantium (immature fruit, extract)Velvet Bean (seed, extract)Bitter Orange (immature Fruit, extract)Nutmeg (seed, extract)Sacred Lotus (leaf, extract) *Daily Values Not Established Other Ingredients: HPMC, White Rice Flour, Magnesium Stearate, Silicon Dioxide Product Highlights Stimulate Fat Loss The S1000-Thermogenic herbal supplement has powerful antioxidant properties and turns your body into a fat burning furnace. This supplement also helps minimize the negative effects of blood sugar spikes caused by the consumption of carbohydrates and may help by improving gut health and enhancing digestion. This product is packed with antioxidants, stress reducers and fat burning herbs such as Bitter Orange, Asian Ginseng and Guarana that will boost your energy and target your fat stores. We’ve carefully crafted a formulation that delivers maximum benefits - try it today to shed fat, increase mood and improve your well being. Manufacturer's Notes Bitter Orange contains small amounts of alkaloids such as synephrine and octopamine, which are direct- and indirect-acting adrenergic agents. Adrenergic agents with beta-agonist activity stimulate lipolysis and increase the resting metabolic rate. Proto-alkaloids found in bitter orange acts as α2 receptor antagonists. α2 receptor activation results in activation of mechanisms associated with the “fight or flight” response, including decreased lipolysis and negative feedback on release of norepinephrine. However, when an antagonist binds the α2 receptor different effects are observed. α2 antagonists are shown to decrease negative feedback resulting in more secretion of norepinephrine, in addition they are also shown to block antilipolytic α2 receptors on adipocytes. This effect acts twofold on lipolysis: first by blocking antilipolytic action, and second by increasing plasma levels of norepinephrine which act on β-3 receptors to activate lipolytic mechanisms. These proto-alkaloids in combination with other adrenergic agents such as synephrine and octopamine has the potential to act synergistically to increase rates of lipolysis, sympathetic tone and may also increase cognitive awareness and arousal. In combination, these compounds can be extremely beneficial as a weight loss aid by taking advantage of pre-existing systems within the human body. This action is also potentiated by methylxanthines, such as caffeine, present in Guarana. Nutmeg contains Myristicin which has been shown to have central nervous system activity and increase brain serotonin levels which results in an increase in satiety. Ginkgo biloba extract has been shown to stabilize mitochondrial activity by stabilization of the mitochondrial membrane and inhibition of cytochrome c release. It also acts upon the apoptotic pathway by upregulation of anti-apoptotic Bcl-2 protein and downregulation of pro-apoptotic Bax protein and reduced level of caspase 9. Panax Ginseng contains ginsenosides which are deglycosylated into compound K which exhibits anti-inflammatory effects by suppressing memory B cell subsets and reducing corticosterone plasma levels. Compound K has also been shown to improve metabolism by balancing blood glucose and increasing insulin sensitivity through up-regulation of insulin receptor substrate 1. Sacred lotus extract reduces body weight, alleviates liver damage and inhibits fat accumulation. Sacred lotus decreases total cholesterol, triglycerides and low-density lipoproteins while increased high-density lipoproteins. Inflammation accompanied by obesity is inhibited by decreasing inflammatory cytokine interleukin (IL)-1β, tumor necrosis factor-α (TNF- α), interferon gamma (IFN-γ) and increasing anti-inflammatory cytokine IL-4 and IL-10 levels. Sacred lotus also increases secretion of bile salts and increases emulsification rate of lipids during digestion. NoticeThese statements have not been evaluated by the FDA.This product is not intended to diagnose, treat, cure or prevent any disease. *California Proposition 65 WARNING: Consuming these products can expose you to chemicals including lead, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.
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