DOPC (26450)

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1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a neutral phospholipid commonly employed as a helper lipid in liposomal formulations for gene and drug delivery. Its unsaturated oleoyl chains confer fluidity to lipid bilayers, promoting the formation of stable lamellar structures that enhance encapsulation and release profiles. When combined with cationic lipids, DOPC plays a synergistic role in improving cellular uptake of nucleic acids and other drug cargo, making it a versatile component in lipid nanoparticle (LNP) formulation. Show more