Read all of this leaflet carefully before you start using this medicine because it contains important information for you. Dulcolax Twelve Plus Suppositories are used for theshort-term relief of occasional constipation. DulcolaxTwelve Plus Suppositories contain bisacodyl whichbelongs to a group of medicines known as stimulantlaxatives, which increase bowel movements. Thismedicine does not help with weight loss.What is constipation?Normal and regular bowel movement is importantfor most people. However, what is “normal andregular” varies from person to person. Some mayhave a bowel movement every day, others less often.Whatever it is like for you, it is best that your bowelmovement has a regular pattern.• Constipation is an occasional problem for somepeople; for others, it may happen more often• It happens when the normal muscle actions in thebowel (large intestine) slow down. This can meanthat the material is not easily eliminated from thebodyThe cause of constipation is often not known. It canbe associated with:• Sudden change of diet• A diet with not enough fibre• Not drinking enough fluids• Loss of ‘tone’ of the bowel muscles in older people• Pregnancy• Medicines such as morphine or codeine• Having to stay in bed for a long time• Lack of exerciseWhatever the cause, constipation is uncomfortable.It may make you feel bloated and heavy, or generally“off colour”. Sometimes it causes headaches.It is recommended to use changes in diet and bulkforming medicines to control constipation beforeusing this medicine.These healthy tips are recommended to try andprevent constipation happening:• Eat a balanced diet including fresh fruit andvegetables• Drink enough water so that you do not becomedehydrated• Keep up your exercise and stay fit• Make time to empty your bowels when your bodytells you Product Information Leaflet