EcoNugenics Honopure delivers 98% pure Honokiol — the neolignin compound isolated from Magnolia officinalis bark that has the most extensive published research of any single compound in the integrative oncology and neuroprotection literature, with over 300 peer-reviewed studies documenting anti-anxiety, neuroprotective, anti-inflammatory, antimicrobial, and cellular health-supporting activities. 120 capsules.Honokiol crosses the blood-brain barrier and blood-spinal cord barrier — a critical and rare property among natural compounds that enables neuroprotective and anxiolytic activity directly in the central nervous system. Published mechanisms include: potent activation of GABA-A receptors (similar to benzodiazepines but without addiction or cognitive impairment); inhibition of NF-κB inflammatory signaling; inhibition of VEGF (tumor angiogenesis); modulation of STAT3 and other oncogenic transcription factors; induction of autophagy in abnormal cells; and significant antioxidant, antimicrobial, and antifungal activity. At 98% purity (vs. standard herbal extracts of 2–10%), Honopure provides the highest bioavailable Honokiol concentration available in a commercial supplement. EcoNugenics is a physician-formulated nutraceutical company founded by integrative oncology expert Isaac Eliaz, M.D., specializing in clinically validated botanical supplements with a focus on Modified Citrus Pectin (MCP) and cellular health. Available at Beauty Riche with same-day shipping.