This is real EGF — not a mimic. Most "growth factor" products on the market use synthetic peptides designed to imitate your skin's renewal signals. The Nurse Jamie EGF Face Cream is built on rh-Oligopeptide-1 — true bioengineered human epidermal growth factor (EGF), molecularly identical to the EGF your own skin produces. Paired with a triple-peptide complex and hyaluronic acid, it's professional-grade growth factor skincare designed for smoother, firmer-looking skin over time. Real EGF vs. growth factor "mimics" It's the difference that defines this cream. When an ingredient list shows rh-Oligopeptide-1 or sh-Oligopeptide-1, the product contains genuine recombinant human EGF — the gold-standard growth factor. Many popular "growth factor serums" instead rely on blends of synthetic peptides (Oligopeptide-1, Hexapeptide, palmitoyl peptides) chosen to mimic growth-factor activity. Both can support the look of healthier skin — but only one is the real thing. What's inside ours: rh-Oligopeptide-1 — true bioengineered human EGF, human-identical structure What's in most "growth factor" serums: peptide blends formulated to imitate growth-factor signals Professional-grade EGF, without the medical-counter price Bioengineered human EGF is the same category of technology found in growth factor serums that sell for $200–$300 at dermatology offices and medical spas. This is the EGF formula designed for Nurse Jamie's professional use in Hollywood — now part of your daily routine at home. What's inside & what it does True Bioengineered EGF (rh-Oligopeptide-1) — human-identical growth factor that supports the look of skin renewal and overall skin quality Triple-Peptide Complex — helps support the appearance of skin firmness and structure over time Hyaluronic Acid — helps maintain hydration and a plump, smooth appearance Apple & Grape Plant Stem Cells — help support a healthy-looking, radiant complexion Shea Butter & Evening Primrose Oil — nourishing botanicals that keep skin feeling soft and comfortable What you'll notice Smoother-looking texture with continued use Hydrated, plump-looking skin — a dewy, refreshed look A more refined, even-looking complexion Lightweight, non-greasy feel — absorbs fast, works beautifully under makeup How to use Cleanse with clean, dry skin to start. Apply a small amount to fingertips. Massage over face and neck in upward strokes until absorbed. Twice daily, morning and evening, for best results. Pair with your roller. Follow with the UpLift face roller to help your skincare absorb. Store the roller in the fridge for a cooling finish. Subscribe & Save Never run out. Subscribe and save up to 20% with free shipping on every delivery — skip or cancel anytime, no commitment. Frequently Asked Questions What is EGF in skincare? EGF stands for Epidermal Growth Factor — a protein that signals skin renewal. In skincare, bioengineered EGF is used to help support the appearance of skin renewal and overall skin quality. Our formula uses rh-Oligopeptide-1, true bioengineered EGF with a human-identical structure. Is this real EGF or a growth factor "mimic"? Real EGF. The active is rh-Oligopeptide-1 — recombinant human epidermal growth factor, molecularly identical to the EGF your skin makes. Many products labeled "growth factor" use synthetic peptides that imitate EGF rather than the genuine ingredient. How is an EGF cream different from a growth factor serum? The active technology is the same family — the difference is the format. This cream delivers bioengineered human EGF alongside peptides, hyaluronic acid, and nourishing botanicals in a daily moisturizer that hydrates while it works, so it can replace a separate moisturizer step. EGF vs. retinol — which should I use? They work differently and can complement each other. Retinol speeds surface turnover (and can irritate sensitive skin); bioengineered EGF supports the look of skin renewal and is gentle enough for most skin types. Many people use EGF in the morning and retinol at night. How long until I see results? Many notice skin feeling more hydrated and smooth within the first few uses. For visible improvements in texture and overall appearance, use consistently for 4–6 weeks. Is it good for sensitive skin? It's formulated to be gentle and suits most skin types. If you have specific sensitivities, patch test first. Can I use it under makeup? Yes — the lightweight, non-greasy formula absorbs quickly and makes a great makeup base. This product is a cosmetic skincare moisturizer, not a medical treatment. It is not intended to diagnose, treat, cure, or prevent any disease or condition. Results refer to the appearance of skin and vary from person to person.
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