EIF2S1 rabbit polyclonal antibody

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Specification Full name EIF2S1 rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]). Swissprot No P05198 Gene Accession NP_004085 WB Predicted band size 36 kDa WB Positive control WB Recommended dilution 200-1000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human cervical cancer IHC Recommed dilution Recommended dilution: 30-150 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P104448-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or EIF2S1 antigen-treated (Neutralization experiment) using P104448(EIF2S1 Antibody) at dilution 1/20 Show more