Elastin from Human Aorta Catalog number: B2019127 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 0.5 mL Molecular Weight or Concentration: N/A Supplied as: Powder Applications: a molecular tool for various biochemical applications Storage: 2-8°C Keywords: Elastin, Human Aortic Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Dave JM, Chakraborty R, Ntokou A, Saito J, Saddouk FZ, Feng Z, Misra A, Tellides G, Riemer RK, Urban Z, Kinnear C, Ellis J, Mital S, Mecham R, Martin KA, Greif DM. JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency J Clin Invest. 2022 Mar 1;132(5):e142338. Heinz A, Schräder CU, Baud S, Keeley FW, Mithieux SM, Weiss AS, Neubert RH, Schmelzer CE. Molecular-level characterization of elastin-like constructs and human aortic elastin Matrix Biol. 2014 Sep;38:12-21. Merla G, Brunetti-Pierri N, Piccolo P, Micale L, Loviglio MN. Supravalvular aortic stenosis: elastin arteriopathy Circ Cardiovasc Genet. 2012 Dec;5(6):692-6. Rebello KR, LeMaire SA, Shen YH. Aortic Neointimal Formation: The Role of Elastin in Conjunction With Vascular Smooth Muscle Cell Origin Arterioscler Thromb Vasc Biol. 2021 Dec;41(12):2906-2908. Song SH, Park HW. Development of elastin layers in the aortic wall of human fetuses Yonsei Med J. 1992 Dec;33(4):337-43. Li B, Lu HS, Daugherty A. Abdominal aortic aneurysms and platelets: infiltration, inflammation, and elastin disintegration Cardiovasc Res. 2024 Mar 30;120(4):331-332. Wanga S, Hibender S, Ridwan Y, van Roomen C, Vos M, van der Made I, van Vliet N, Franken R, van Riel LA, Groenink M, Zwinderman AH, Mulder BJ, de Vries CJ, Essers J, de Waard V. Aortic microcalcification is associated with elastin fragmentation in Marfan syndrome J Pathol. 2017 Nov;243(3):294-306. Pukaluk A, Wolinski H, Viertler C, Regitnig P, Holzapfel GA, Sommer G. Changes in the microstructure of the human aortic adventitia under biaxial loading investigated by multi-photon microscopy Acta Biomater. 2023 Apr 15;161:154-169. Tsamis A, Krawiec JT, Vorp DA. Elastin and collagen fibre microstructure of the human aorta in ageing and disease: a review J R Soc Interface. 2013 Mar 27;10(83):20121004.
