eosinophil necklace | sterling silver If you have ever called out an eosinophil on a peripheral blood smear, you know the cell by sight. Two-lobed nucleus and bright pink granules so dense they catch the dye like nothing else on the slide. The cell that announces itself before you label it. How Eosinophils Work Eosinophils are granulocytic white blood cells that make up roughly 1-4% of circulating leukocytes in healthy adults. Their cytoplasmic granules contain major basic protein, eosinophil cationic protein, and other cytotoxic molecules selected over evolution against parasites that are too large to be phagocytosed (helminths and other multicellular parasites). In modern medicine, eosinophils are mostly clinically relevant in allergic disease, asthma, eosinophilic oesophagitis, and certain autoimmune conditions. Eosinophilia (an elevated eosinophil count) is a routine flag on any complete blood count. The biology was first characterised by Paul Ehrlich in 1879, who used the eosin dye that gives the cell its name and a Nobel-winning research career its early footing. Who Will Recognise It Mostly clinicians and researchers who watch eosinophils for a living. haematologists and laboratory medicine specialists allergists and asthma clinicians immunologists and parasitology researchers medical technologists running blood smears respiratory physicians working on eosinophilic asthma Often given to medical residents finishing haematology rotations or to allergy and immunology fellows finishing fellowship training. Explore Related Cellular Biology Jewelry red blood cells necklace | silver macrophage necklace | silver neutrophil necklace | silver monocyte necklace | silver FAQ Is this specific enough for a real haematologist? Yes. The cell type is recognisable on a single glance at any peripheral smear, and the morphology is one of the first taught in medical haematology. If the recipient has spent any clinical time reading complete blood counts or thinking about allergy and parasitology, the piece is a peer-level reference. Outside laboratory medicine, expect to explain. Why does the cell stain so vividly with eosin? The granules are packed with strongly basic proteins, particularly major basic protein and eosinophil cationic protein. Eosin is an acidic dye, and acidic dyes bind tightly to basic proteins. The pairing is so consistent that "eosinophilic" became the standard descriptor for any cell or structure that takes up eosin readily, long before the underlying biochemistry was worked out. Size, material, chain length? 16 mm pendant in 925 polished sterling silver, nickel-free and hypoallergenic, on a 45 cm sterling silver chain (1.8 mm diameter) with lobster clasp and a 5 cm extender. Free DHL Express shipping worldwide in 1-5 business days, all duties and taxes covered, 30-day “Love It or Return It” policy. Is there a gold or other material version? Not currently. The eosinophil necklace exists only in sterling silver. A gold vermeil or solid gold version can be made on request through our custom design service (around 4-6 weeks total).
Related
Related
Related
Related