Specification Full name FBXO32 rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. Swissprot No Q969P5 Gene Accession NP_478136 WB Predicted band size 42 kDa WB Positive control WB Recommended dilution 200-1000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human prostate cancer IHC Recommed dilution Recommended dilution: 50-100 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P112729-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or FBXO32 antigen-treated (Neutralization experiment) using P112729(FBXO32 Antibody) at dilution 1/20
