Since its inception the de Mamiel brand has been built around EPiC - the three pillars of stress: emotional, physical and cellular. So, it came as no surprise to us that Annee de Mamiel would be among the first in world to create a serum that treats both the causes and symptoms of stress on our skin. First Fix is the result of 13 years of dedicated research and development. Recently, science has taught us that our skin cells cannot only perceive stress on their own, but that they can also directly produce cortisol. Cortisol production from the skin cell can compromise barrier function, leave the skin looking dull, feeling dehydrated and irritated, and showing unwanted signs of premature aging. Containing a host of effective and reparative plant actives and extracts, this powerful serum will soothe, protect and repair skin back to health. In addition to finding some of the best ingredients found worldwide, de Mamiel has created the de Mamiel Cortisol Resilience Complex™ to address the emotional impact of stress. This aromatherapeutic blend triggers a change in the way we respond to stress. 89% of testers said their skin felt more HYDRATED 80% of testers said their skin appeared more RADIANT 88% of testers said their skin felt SMOOTHER Suitable for all skin types, including those with sensitive skin.