FRIO the world’s first patented cooling wallet – Simply activate with cold water!– Light and compact– Reusable All FRIO wallets have been designed with our patented crystal technology to keep your temperature sensitive medication cool and safe. The FRIO Large Wallet is perfect for a variety of different types of insulin pen, insulin vials or cartridges and auto-injector making this particular FRIO ideal for those with conditions such as Diabetes, Rheumatoid Arthritis, Crohn’s Disease and Anaphylaxis. With a minimum continuous cool period of 45 hours and a recharge time of under 5 minutes, FRIO is made for your everyday – wherever that might be! Suitable for carrying the following combinations of pens, vials and cartridges: Diabetes Medication– up to 5 standard sized insulin injection pens either pre-filled disposable or refillable; or– up to 10 x 3 ml cartridges; or– up to 15 x 1.5 ml cartridges; or– up to 5 x 10 ml vials (bottles); or– a combination of pens, vials and cartridges Anaphylaxis Medication– up to 3 x EpiPens (Adrenaline: for emergency treatment of anaphylactic reactions) Rheumatoid Arthritis and Crohn’s Disease Medication– up to 4 x Enbrel® pens