Treats bacterial infections Safe for aquarium plants Safe for shrimp, snails, and other invertebrates Fritz Maracyn® is a specially compounded broad-spectrum antibiotic (erythromycin) which has been shown to be effective against a number of pathogenic bacteria associated with ornamental fish disease. It was developed for complete but gradual dissolution in water. It is primarily effective against gram-positive pathogenic organisms. Symptoms of clamped fins, swollen eyes, heavy or rapid breathing, patchy coloration, change in swimming behavior or corner-hiding can be signs of possible bacterial infection. For the 10-count and 20-count boxes of Maracyn, the medication comes in individual packets where each packet treats 10 gallons of water. The 100-gram bulk container treats a total of 1,000 gallons of water while the 400-gram bulk container treats 4,700 gallons of water, and both containers come with a scoop for easy dosing. When treating with Maracyn, we recommend using an air stone in the aquarium, which may temporarily cause excessive foaming at the water surface. Directions/Specifications For best results, we recommend removing chemical filtration from your aquarium filter before dosing the medication. Examples of chemical filtration include activated carbon, carbon-infused media pads, Seachem Purigen, phosphate media pads, and ammonia media pads. Manufacturer's Directions on the Package:One complete course of treatment will take 5 days. Treat for the full course of treatment even if visible signs of infection or illness disappear.— Day One through Day Five: Each day, add contents of one packet per 10 gallons of water to be treated. For the bulk jar, add 1 level scoop (approximately 1 gram) per 10 gallons of water each day.— Day Six: Perform a 25% water change. If necessary, a second full course of treatment may be performed starting on Day Seven. Aquarium Co-Op Instructions:Dose one packet (or 1 level scoop from the bulk jar) per 10 gallons of water to be treated. Let sit in aquarium for 7 days. Then do 25% water change. Notes:— All suspected bacterial infections should be treated immediately.— Fritz Maracyn® is non-toxic to invertebrates such as snails and shrimp.— Don't confuse this medication with Maracyn 2, which is not the same medication.