Specification Full name GAPDH rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] (The background information is obtained from official databases and does not represent the product information.) Swissprot No P04406 Gene Accession BC001601 WB Predicted band size 36 kDa WB Positive control WB Recommended dilution 5000-20000 IHC predicted cell location Predicted cell location: Cytoplasm and Nucleus IHC positive control Positive control: Human liver cancer IHC Recommed dilution Recommended dilution: 50-200 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P100001-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or GAPDH antigen-treated (Neutralization experiment) using P100001(GAPDH Antibody) at dilution 1/75
