NPN: 80076946Helps to temporarily increase feelings of fullness.Herbal Magic’s Garcinia Extract has been formulated to help temporarily increase satiety (fullness) to support weight management. This formula contains the key ingredient Hydroxycitric Acid (HCA), which has been shown to reduce appetite, inhibit fat synthesis and decrease body weight without stimulating the central nervous system. Core program product for clients aged 19+ in the Motivation and Determination stages of their weight loss programs. Optional product for those experiencing hunger and struggling to comply with their program’s menu plan. Garcinia Extract helps reduce appetite by sending satiety (fullness) signals to the brain, helps control emotional eating, and helps inhibit your body’s ability to convert sugar into fat.Each capsule provides two types of Garcinia extracts that help support appetite control - the key component being Hydroxycitric Acid (HCA).PRODUCT MONOGRAPH FOR HERBAL MAGIC Garcinia Extract NPN 80076946GENERAL INFORMATION Herbal Magic’s Garcinia Extract has been formulated to help to temporarily increase satiety to support weight management. This formula contains the key ingredient Hydroxycitric Acid (HCA), which has been shown to reduce appetite, inhibit fat synthesis and decrease body weight without stimulating the central nervous system.RECOMMENDED USES Primary Use: Helps to temporarily increase feelings of fullness.MECHANISM OF ACTION Research Suggests (-)-Hydroxycitric acid (HCA)(-)-Hydroxycitric acid (HCA) is a principle component of the dried fruit rind of Garcinia cambogia, a plant native to Southeastern Asia. The dried rind has been used for centuries throughout Southeast Asia as a food preservative, flavouring agent and digestive aid.1Research shows that Garcinia extract helps control satiety and support weight-loss by modulating serotonin levels and fat synthesis to suppress appetite. HCA helps stimulate serotonin release and inhibit reuptake in the body. Serotonin (5-HT) is a neurotransmitter involved in several behavioural functions within the body, including mood and appetite control. Studies show that serotonin impacts eating behavior and body weight; increased circulating levels are associated with lower food intake, reduced weight gain and increased energy expenditure.2,3,4 Therefore, increased serotonin levels can help address many of the emotional issues overweight people face.5,6HCA has also been shown to be a competitive inhibitor of ATP-citrate lyase, a key player in the conversion of citrate into acetyl coenzyme A, a primary building block for fatty acid synthesis. Inhibiting ATP-citrate lyase directs carbohydrates away from fat synthesis and towards storing energy in the form of glycogen. Increased glycogen levels send satiety signals to the brain, ultimately leading to reduced food intake.7A 2 week study showed that 500 mg of SuperCitriMax® decreases calorie intake and sustains satiety. In a randomized, placebo-controlled, crossover study, 24 overweight men and women consumed SuperCitriMax® an hour before lunch and dinner and two hours after dinner for two weeks. SuperCitriMax® significantly decreased 24-hour energy intake by 25% and snacking by 40% compared to placebo. SuperCitriMax® also decreased calorie intake at every meal, while satiety was sustained, and demonstrated a reduction in body weight of 1.1 pounds.8Another randomized placebo-controlled study also demonstrated that 1500 mg of Garcinia Extract daily taken before meals for eight weeks resulted in 215% greater weight loss than placebo, and a significant reduction was in cholesterol and triglyceride levels was also observed.9RECOMMENDED DOSAGE For Ages 18+: 1 cap 3x/day before meals, a few hours before or after other medications.CAUTIONS AND WARNINGS If you are pregnant or breastfeeding, consult a health care practitioner prior to use.DISEASE/CONDITION INTERACTIONS No statement.DRUG INTERACTIONS No statement.FORMULATION Medicinal Ingredients: Malabar tamarind fruit rind extract (5:1) (Garcinia cambogia) ………………………………………………….. 200 mg (1000 mg crude) Standardized to 60% Hydroxycitric acid SuperCitrimax® Calcium-Potassium Salt of Hydroxycitric Acid (Garcinia cambogia fruit rind) .......................................... 500 mg Standardized to 60% Hydroxycitric acid, 11% Calcium and 16% PotassiumNon-medicinal Ingredients: Hypromellose, Magnesium stearate, and Microcrystalline cellulose.Features:Non-GMOVegan friendlyGluten freeDye Free REFERENCE 1 Soni, M. G., Burdock, G. A., Preuss, H. G., Stohs, S. J., Ohia, S. E., & Bagchi, D. (2004). Safety assessment of (−)-hydroxycitric acid and Super CitriMax®, a novel calcium/potassium salt. Food and Chemical Toxicology,42(9), 1513-1529. 2 Jena BS, Jayaprakasha JK, Singh RP, Sakariah KK, Chemistry and Biochemistry of (–)-Hydroxycitric Acid from Garcinia, Journal of Agricultural and Food Chemistry 50:10-22, 2002. 3 Leibowitz SF and Alexander JT, Hypothalamic Serotonin in Control of Eating Behavior, Meal Size, and Body Weight, Society of Biological Psychiatry, 44: 851-864, 1998. 4 Casper RC, Serotonin, A Major Player in the Regulation of Feeding and Affect, Society of Biological Psychiatry, 44:795-797, 1998. 5 Mauri MC, Rudelli R, Somasehini E, Roncoroni L, Papa R, Mantero M, Penati G, Neurobiological and Psychopharmacolgical Basis in the Therapy of Bulimia and Anorexia, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 20:207-240, 1996. 6 Wilding J, Widdowson P, Williams G, Neurobiology, British Medical Bulletin, 53:286-306, 1997. 7 Sullivan AC, Triscari J, Hamilton JG, Miller ON, Wheatley VR, Effect of (-)-Hydroxycitrate upon the Accumulation of Lipid in the Rat. I. Lipogenesis, Lipids, 9:121-128, 1974. 8 Westerterp-Plantenga MS, Kovacs EMR. The effect of (-)-hydroxycitrate on energy intake and satiety in overweight humans. Int J Obes Relat Metab Disord. 2002 June; 26(6): 870–872. 9 Ramos RR, Saenz JLS, Aguilar RJA, Extract of Garcinia cambogia in Controlling Obesity, Investigacion Medica Internacional. 22:97-100, 1995
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