Generic Fluorogenic Proteases Substrate Catalog number: B2011245 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 5 mg Molecular Weight or Concentration: na Supplied as: Lyophilized Applications: molecular tool for various biochemical applications Storage: -20 °C Keywords: (Z-Arg)2Rh110 Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Rut W, Kasperkiewicz P, Byzia A, Poreba M, Groborz K, Drag M. Recent advances and concepts in substrate specificity determination of proteases using tailored libraries of fluorogenic substrates with unnatural amino acids Biol Chem. 2015 Apr;396(4):329-37. Sha Z, Fishovitz J, Wang S, Chilakala S, Xu Y, Lee I. A Selective Fluorogenic Peptide Substrate for the Human Mitochondrial ATP-Dependent Protease Complex ClpXP Chembiochem. 2020 Jul 16;21(14):2037-2048. Arian D, Harenberg J, Krämer R. A Chromogenic and Fluorogenic Peptide Substrate for the Highly Sensitive Detection of Proteases in Biological Matrices J Med Chem. 2016 Aug 25;59(16):7576-83. Al-Abdullah IH, Bagramyan K, Bilbao S, Qi M, Kalkum M. Fluorogenic Peptide Substrate for Quantification of Bacterial Enzyme Activities Sci Rep. 2017 Mar 13;7:44321. Tichá A, Stanchev S, Škerle J, Began J, Ingr M, Švehlová K, Polovinkin L, Růžička M, Bednárová L, Hadravová R, Poláchová E, Rampírová P, Březinová J, Kašička V, Majer P, Strisovsky K. Sensitive Versatile Fluorogenic Transmembrane Peptide Substrates for Rhomboid Intramembrane Proteases J Biol Chem. 2017 Feb 17;292(7):2703-2713. Harris JL, Backes BJ, Leonetti F, Mahrus S, Ellman JA, Craik CS. Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7754-9. Gosalia DN, Salisbury CM, Ellman JA, Diamond SL. High throughput substrate specificity profiling of serine and cysteine proteases using solution-phase fluorogenic peptide microarrays Mol Cell Proteomics. 2005 May;4(5):626-36. Garreto L, Charneau S, Mandacaru SC, Nóbrega OT, Motta FN, de Araújo CN, Tonet AC, Modesto FMB, Paula LM, de Sousa MV, Santana JM, Acevedo AC, Bastos IMD. Mapping Salivary Proteases in Sjögren’s Syndrome Patients Reveals Overexpression of Dipeptidyl Peptidase-4/CD26 Front Immunol. 2021 Jun 17;12:686480. Stawikowski MJ, Knapinska AM, Fields GB. Determining the Substrate Specificity of Matrix Metalloproteases using Fluorogenic Peptide Substrates Methods Mol Biol. 2017;1579:137-183.
