Glucose Manager, Premier

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Premier Research Labs Glucose Manager, Premier Advanced Blood Sugar & Metabolic Health Support This dual-mechanism formula combines clinically validated ingredients for comprehensi ve glucose regulation and metabolic support. GlucoVantage® Dihydroberberine (100mg)—with 5x greater bioavailability than berberine—activates the body's normal AMPK pathways to support insulin sensitivity, lipid metabolism, and mitochondrial function. Reducose® Mulberry Extract (250mg, standardized to 12mg DNJ) inhibits alpha-glucosidase to attenuate postprandial glucose excursions. Key Benefits: Promotes insulin sensitivity and enhanced cellular glucose uptake Supports healthy lipid metabolism and cholesterol balance Enhances metabolic flexibility and cellular energy production More microbiome-friendly than traditional berberine for comfortable long-term use Supports healthy fasting glucose levels already within the normal range Ingredients Serving Size: 1 Vegetarian Capsule Amount/Serving GlucoVantage® (Dihydroberberine) 100 mg Reducose® (from Mulberry Leaf Extract) (Morus alba) (standardized to contain 5% 1-deoxynojirimycin) 250 mg Other Ingredients: Plant-Source Capsule (cellulose, water), Rice Bran (Non-GMO). Does Not Contain: GMOs, gluten, soy, dairy, fillers, stearates, or artificial colors. Non-GMO, Gluten-Free, Soy-Free, Dairy-Free, Vegan, Vegetarian Suggested Use Take 2 capsules with every meal with carbohydrates, maximum 3 capsules a day, or as directed by a healthcare professional. Warning: Use only if the seal is intact. Consult your health care practitioner if you are pregnant or nursing, taking medications, or have a medical condition, before taking this or any other product. If you are taking glucose-lowering medications, consult your healthcare provider before use, as this product may have additive effects. Dihydroberberine may interact with medications metabolized by CYP450 enzymes or P-glycoprotein. Keep out of reach of children. Well-tolerated at recommended doses. The enhanced bioavailability of GlucoVantage® DHB helps minimize gastrointestinal distress commonly associated with traditional berberine supplements. Storage: Store in a cool, dry place. More Info. Synergistic Formulation with clinically studied ingredients to support balanced blood sugar already within the normal range Reducose® (Mulberry Leaf Extract) has been clinically shown to support post-meal glucose and insulin responses. GlucoVantage® (Dihydroberberine) has been clinically shown to be approximately 5X more bioavailable than standard berberine GlucoVantage® (Dihydroberberine) supports healthy lipid metabolism and cardiovascular health A dual-mechanism approach to glycemic management, combining two clinically validated ingredients at evidence-based doses. Glucose Manager pairs GlucoVantage® Dihydroberberine with Reducose® Mulberry Extract to address glucose dysregulation at both the intestinal and cellular levels, providing comprehensive metabolic support across the full glycemic cycle.Why Glucose Manager Works DifferentlyMost glucose support products target only one aspect of blood sugar management. Glucose Manager takes a comprehensive approach by addressing both glucose absorption and cellular utilization, providing complete metabolic coverage across your entire glycemic cycle. This professional-grade formulation pairs two trademarked, clinically researched ingredients at their scientifically validated doses. The Power of Two Premium IngredientsGlucoVantage® Dihydroberberine (100 mg per capsule) GlucoVantage® represents a significant advancement in berberine supplementation. This hydrogenated derivative of berberine offers superior bioavailability – up to 5 times greater absorption than standard berberine – allowing for lower doses with enhanced effectiveness and improved tolerability.How It Works: Dihydroberberine (DHB) activates AMPK, often called your body's "master metabolic switch." This activation helps enhance insulin sensitivity, supports healthy cellular glucose uptake, and promotes efficient energy metabolism in your muscles and liver. With an extended half-life of 4-6 hours, DHB provides sustained metabolic support throughout your day. Reducose® Mulberry Leaf Extract (250 mg per capsule)Reducose® is a premium mulberry leaf extract standardized to 5% 1-Deoxynojirimycin (DNJ) – delivering 12.5 mg of this clinically studied compound per dose. This represents 50 times the DNJ content of typical mulberry extracts, ensuring therapeutic potency backed by over a decade of human clinical research. How It Works: The active compound DNJ naturally inhibits alpha-glucosidase enzymes in your small intestine, slowing the breakdown of complex carbohydrates into simple sugars. This action effectively converts high-glycemic foods into low-glycemic equivalents, smoothing your post-meal glucose curve and reducing insulin demand. Key Benefits: Helps reduce post-meal glucose spikes by up to 40% May reduce insulin response by up to 41%, supporting healthy pancreatic function Supports healthy blood sugar balance after carbohydrate-containing meals Enhances insulin signaling pathways for improved glucose metabolism Extracted using a pure water process with no harsh solvents Show more