Product Details What is Glucuronolactone Powder? Glucuronolactone is a natural component found in most connective tissues, such as cartilage, ligaments, and tendons. It’s also essential to synthesize chondroitin sulfate—a compound that promotes joint health. Glucuronolactone converts into glucuronic acid, which helps produce amino acids, fatty acids, and DNA components by breaking down and detoxing glucose. Glucuronolactone may support liver health and cognitive function. It’s a common ingredient in sports and energy drinks, as it boosts energy and enhances athletic performance. The body can synthesize glucuronolactone in the liver by breaking down glucose. However, it can only produce small amounts at a time. Potential Glucuronolactone Benefits Glucuronolactone and Exercise Performance Sports and energy drinks often include glucuronolactone for its ability to boost energy and enhance athleticism. Studies examining these beverages noted improvements in aerobic, anaerobic, and physical endurance. Participants experienced dramatic improvements in sustaining their max heart rate and their max speed while cycling. Researchers believe glucuronolactone acts as an additional energy source during intense physical activity. It also helps prevent exercise fatigue by attenuating the effects of energy depletion. Glucuronolactone may help build lean muscle. It synergizes with other pre-workout supplements to increase the number of repetitions individuals can perform during resistance training and boost their power output. Glucuronolactone and Cognitive Function Glucuronolactone may benefit cognitive performance in addition to enhancing athleticism. Researchers noted that energy drinks containing glucuronolactone dramatically improved participants’ choice reaction time, concentration, and memory recall. Participants also experienced an increase in mental alertness. Other studies have noted reductions in mental strain and improvements in attention. Glucuronolactone and Resveratrol Taking glucuronolactone with resveratrol may support heart health. D-glucaro-1,4-lactone has antioxidant properties and synergizes with resveratrol to protect blood vessels against free radicals. Glucuronolactone is also an anti-platelet compound. Glucuronolactone and Liver Health Glucuronolactone may support liver health by binding to environmental toxins and cell-damaging molecules. It helps detoxify these compounds by enhancing their solubility, reducing their toxicity, and facilitating their faster excretion. Glucuronolactone also breaks down into D-glucaro-1,4-lactone. D-glucaro-1,4-lactone inhibits beta-glucuronidase enzymes from slowing the detox process. It also reduces inflammation and markers of liver injury. Potential Glucuronolactone Side Effects Individuals that primarily consume glucuronolactone through energy drinks may experience side effects due to the other ingredients in the beverage. Many energy drinks contain caffeine and can lead to headaches, stomach upset, and sleep disruption if individuals consume too much of it. Most individuals tolerate glucuronolactone supplements well. References https://journals.humankinetics.com/doi/pdf/10.1123/att.12.2.43 https://www.ncbi.nlm.nih.gov/pubmed/29212304 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1264951 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082800 https://pubmed.ncbi.nlm.nih.gov/11665810 https://www.researchgate.net/publication/17865627_Effects_of_glucuronolactone_and_the_other_carbohydrates_on_the_biochemical_changes_produced_in_the_living_body_of_rats_by_hard_exercise https://www.ncbi.nlm.nih.gov/pubmed/18438227 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761845 https://pubmed.ncbi.nlm.nih.gov/18438227 https://www.ncbi.nlm.nih.gov/pubmed/29484974 https://www.ncbi.nlm.nih.gov/pubmed/28266877 https://www.ncbi.nlm.nih.gov/pubmed/11465080 https://www.ncbi.nlm.nih.gov/pubmed/24480360 https://www.ncbi.nlm.nih.gov/pubmed/15323223 https://www.ncbi.nlm.nih.gov/pubmed/21063868 https://www.ncbi.nlm.nih.gov/pubmed/11140366 https://www.sciencedirect.com/science/article/pii/S089990070600390X?via%3Dihub#bib48 https://www.sciencedirect.com/science/article/pii/S0939475307000890 https://link.springer.com/article/10.1007%2Fs10565-007-9028-8 https://www.sciencedirect.com/science/article/pii/S1756464615000304#bib0070 https://www.ncbi.nlm.nih.gov/pubmed/17846905 https://www.ncbi.nlm.nih.gov/pubmed/17933501 https://www.ncbi.nlm.nih.gov/pubmed/17234507 Tested by Accredited 3rd Party Labs PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here. *NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
