Ultimate Glutathione

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Formula Purposes & Benefits Ultimate Glutathione is developed based on cutting-edge scientific research and expert formulation to support healthy detoxification, immune health, inc reased antioxidant status, healthy aging, improved exercise performance, cognitive health, and improved body composition. Our formula utilizes the reduced and bioavailable form, glutathione GSH providing world class glutathione support and bioavailability. Ultimate Glutathione contains a botanical blend called PhytoActiv Support™. PhytoActiv Support™ consists of various botanical agents that are biocompatible and offer a diverse range of phytochemicals providing additional nutritional support, contributing to overall well-being. Our formula is proudly made in the USA in an FDA registered facility, following Good Manufacturing Practices (GMP) standards. Our commitment to excellence is reflected in the fact that only 4% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Glutathione ● May support antioxidant activity via increased L-cysteine formation, increased free radical scavenging, and increased neutralization of pro-inflammatory free radicals (401,402). ● •May support immune health via increased generation of anti-inflammatory nutrients such as vitamin c and vitamin e (401,402). ● May support immune health via increases in plasma free circulating glutathione levels (401,402). ● May support total body health via increased cellular repair and regeneration (401,402). ● May support healthy aging via correcting GSH deficiency, reduced mitochondrial dysfunction; reduced oxidative stress, reduced oxidant damage (401,402). ● May support cardiovascular health via reduced inflammation, insulin resistance, endothelial dysfunction, and genotoxicity (401,402). ● May support exercise performance via increased muscle strength, gait speed, exercise capacity, and cognitive health (401,402). ● May support body composition via reduced activity in degradative protein pathways (401,402). Organic Turmeric ● May support antioxidant, cardio-protective, anti-inflammatory, anti-microbial, nephro-protective, hepato-protective, immunomodulatory, and anti-rheumatic effects (123). ● May reduce inflammation via decreases of inflammatory markers such as c-reactive protein, interleukin 6, tumor necrosis factor, and decreased cytokine production (123). ● May support joint health via decreases in connective tissue inflammation and improved pain in individuals with osteoarthritis (122). ● May support blood sugar regulation via increased pancreatic beta cell function and improved insulin sensitivity (121). ● May support cardiovascular and liver health via reduced accumulation of advanced glycation end products (AGE), reduced lipid peroxidation, and improved vascular function. ● Curcumin may exhibit antioxidant activity via scavenging of superoxide anion (∙O2−∙) and hydroxyl radicals (∙OH) (scavenging of inflammation molecules) (118,119). ● Curcumin may modulate breast carcinogenesis through its effect on cell cycle and proliferation, apoptosis, senescence, cancer spread and angiogenesis (119). Aquamin® Mineralized Red Algae ● May support osteogenesis, promoting bone formation and mineralization (390). ● May support antioxidant effects and the ability to induce apoptosis in U937 cells (392). ● May support enhanced gut microbial diversity, potentially promoting digestive health (393). ● May support improvements in lipid profiles, including potentially lowering LDL cholesterol levels (394). Reishi ● May support immune health, antioxidant activity, balanced estrogen levels, antiviral support, antibacterial, reduced stress, improved exercise performance, and blood sugar regulation (194,195). ● May support immune health via high concentrations of betagluxans which increase natural killer cell activity and t-cell mediated immunity (194). Organic Hyssop ● May support respiratory health, digestive health, healthy detoxification, and may combat respiratory viruses (272). Organic Burdock Root ● May support healthy detoxification, cardiovascular health, skin health, and immune health (356). ● May support immune health through its high levels of antioxidants, polyphenols, and flavonoids, which enhance the adaptive/innate immune response (356). ● May support cardiovascular and skin health by promoting enhanced blood circulation to the skin surface, improving skin quality, and potentially combating skin diseases (356). ● May support antioxidant function through the presence of antioxidant and antidiabetic compounds found in the root, which possess anti-inflammatory effects and potent inhibitory effects that may inhibit malignant growth (356). Organic Fennel ● May support joint health via decreased prevalence of intense arthritic symptoms (390). Lemon Peel ● May support healthy sleep, relaxation, reduced anxiety, and antioxidant support (254,255). ● May support antioxidant function via ability to scavenge free radicals, reduce oxidative stress, increased glutathione production (master antioxidant) combat DNA damage (254,225). ● May support relaxed sleep via enhanced REM cycles reduced stress at bedtime (254,225). Proper Use of This Supplement Suggested Use: Take 1 capsule, 3 times daily, or as directed by a health professional. Our Formula Vs Other Formulas on the Market. 1. Our formula is GMP certified and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. 2. High quality glutathione in a bioavailable and efficaciously dosed formula utilizing PhytoActiv Support™ technology. 2. Uses cheap glutathione that may have heavy metals due to poor product quality and fillers. Sources: Sartore, G. (2016). Curcumin and Boswellia serrata Modulate the Glyco-Oxidative Status and Lipo-Oxidation in Master Athletes. Nutrients, 8(11), 745. https://doi.org/10.3390/nu8110745 Barzegar, A., & Moosavi-Movahedi, A. A. (2011). Intracellular ROS protection efficiency and free radical-scavenging activity of curcumin. PloS one, 6(10), e26012. https://doi.org/10.1371/journal.pone.0026012 Banik, U., Parasuraman, S., Adhikary, A. K., & Othman, N. H. (2017). Curcumin: the spicy modulator of breast carcinogenesis. Journal of experimental & clinical cancer research : CR, 36(1), 98. https://doi.org/10.1186/s13046-017-0566-5 Suhett, L. G., de Miranda Monteiro Santos, R., Silveira, B., Leal, A., de Brito, A., de Novaes, J. F., & Lucia, C. (2021). Effects of curcumin supplementation on sport and physical exercise: a systematic review. Critical reviews in food science and nutrition, 61(6), 946–958. https://doi.org/10.1080/10408398.2020.1749025 Pivari, F., Mingione, A., Brasacchio, C., & Soldati, L. (2019). Curcumin and Type 2 Diabetes Mellitus: Prevention and Treatment. Nutrients, 11(8), 1837. https://doi.org/10.3390/nu11081837 Ashtary-Larky, D., Rezaei Kelishadi, M., Bagheri, R., Moosavian, S. P., Wong, A., Davoodi, S. H., Khalili, P., Dutheil, F., Suzuki, K., & Asbaghi, O. (2021). The Effects of Nano-Curcumin Supplementation on Risk Factors for Cardiovascular Disease: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical Trials. Antioxidants (Basel, Switzerland), 10(7), 1015. https://doi.org/10.3390/antiox10071015 Mata, I., Mata, S., Menezes, R., Faccioli, L. S., Bandeira, K. K., & Bosco, S. (2020). Benefits of turmeric supplementation for skin health in chronic diseases: a systematic review. Critical reviews in food science and nutrition, 1–15. Advance online publication. https://doi.org/10.1080/10408398.2020.1798353 Hetland G, Tangen JM, Mahmood F, Mirlashari MR, Nissen-Meyer LSH, Nentwich I, Therkelsen SP, Tjønnfjord GE, Johnson E. Antitumor, Anti-Inflammatory and Antiallergic Effects of Agaricus blazei Mushroom Extract and the Related Medicinal Basidiomycetes Mushrooms, Hericium erinaceus and Grifolafrondosa: A Review of Preclinical and Clinical Studies. Nutrients. 2020 May 8;12(5):1339. doi: 10.3390/nu12051339. PMID: 32397163; PMCID: PMC7285126. Mallard B, Leach DN, Wohlmuth H, Tiralongo J. Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake. PLoS One. 2019 Nov 7;14(11):e0224740. doi: 10.1371/journal.pone.0224740. PMID: 31697749; PMCID: PMC6837746. Miraj S, Rafieian-Kopaei, Kiani S. Melissa officinalis L: A Review Study With an Antioxidant Prospective. J Evid Based Complementary Altern Med. 2017 Jul;22(3):385-394. doi: 10.1177/2156587216663433. Epub 2016 Sep 11. PMID: 27620926; PMCID: PMC5871149. Taavoni S, Nazem Ekbatani N, Haghani H. Valerian/lemon balm use for sleep disorders during menopause. Complement Ther Clin Pract. 2013 Nov;19(4):193-6. doi: 10.1016/j.ctcp.2013.07.002. Epub 2013 Sep 10. PMID: 24199972. Hyssop. (2018). In LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., & Chan, S. W. (2011). A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology, 19(5), 245–254. https://doi.org/10.1007/s10787-010-0062-4 Widaa, A., Brennan, O., O'Gorman, D. M., & O'Brien, F. J. (2014). The osteogenic potential of the marine-derived multi-mineral formula aquamin is enhanced by the presence of vitamin D. Phytotherapy Research, 28(5), 678-684. doi: 10.1002/ptr.5038 391.O'Callaghan, Y. C., Drummond, E., O'Gorman, D. M., & O'Brien, N. M. (2013). Antioxidant and pro-apoptotic effects of marine-derived, multi-mineral aquamin supplemented with a pine bark extract, Enzogenol, and a green tea extract, Sunphenon. Journal of Medicinal Food, 16(10), 920-926. doi: 10.1089/jmf.2012.0258 Crowley, E. K., Long-Smith, C. M., Murphy, A., Patterson, E., Murphy, K., O'Gorman, D. M., Stanton, C., & Nolan, Y. M. (2018). Dietary supplementation with a magnesium-rich marine mineral blend enhances the diversity of gastrointestinal microbiota. Marine Drugs, 16(6), 216. doi: 10.3390/md16060216 394.Cronin, B. E., Allsopp, P. J., Slevin, M. M., Magee, P. J., Livingstone, M. B. E., Strain, J. J., & McSorley, E. M. (2016). Effects of supplementation with a calcium-rich marine-derived multi-mineral supplement and short-chain fructo-oligosaccharides on serum lipids in postmenopausal women. British Journal of Nutrition, 115(4), 658-665. doi: 10.1017/S0007114515004948 Sekhar R. V. (2021). GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging. The Journal of nutrition, 151(12), 3606–3616. https://doi.org/10.1093/jn/nxab309 Sinha, R., Sinha, I., Calcagnotto, A., Trushin, N., Haley, J. S., Schell, T. D., & Richie, J. P., Jr (2018). Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function. European journal of clinical nutrition, 72(1), 105–111. https://doi.org/10.1038/ejcn.2017.132 Show more