Advanced Peptide Regeneration System™ A Next-Generation Peptide Signaling Cream Designed to Support Visible Skin Renewal, Hydration, and Healthy Aging Most topical products moisturize the skin. FACEgevity™ is designed to signal it. Conventional anti-aging creams work at the surface — adding moisture, occluding the barrier, or delivering generic antioxidants. FACEgevity™ is designed differently. Every peptide in this formula has a specific biological target: a signaling pathway, a gene expression mechanism, a cellular process tied to how skin ages at the structural level. The result is not a cosmetic that hides the signs of aging. It is a precision system designed to support the biology that determines how your skin ages.* Unlike conventional anti-aging creams that focus on isolated ingredients, FACEgevity™ delivers multiple complementary signaling pathways designed to support: Skin firmness and elasticity Hydration and barrier integrity The appearance of fine lines and expression lines Healthy collagen architecture Skin resilience and recovery A more youthful-looking complexion The FACEgevity™ Multi-Peptide Regenerative Signaling Complex™ FACEgevity™ combines six complementary bioactive ingredients selected to support skin architecture, hydration, barrier integrity, and healthy aging through multiple peptide signaling pathways. GHK-Cu (3%) GHK-Cu (glycyl-L-histidyl-L-lysine-copper) is a naturally occurring tripeptide first identified in human plasma, where its concentration of approximately 200 µg/L at age 20 declines significantly with age. It acts as both a signal and carrier peptide, supporting extracellular matrix remodeling, promoting collagen, elastin, proteoglycan, and glycosaminoglycan synthesis, and exerting antioxidant and anti-inflammatory effects. At 3% concentration, FACEgevity™ delivers a clinically meaningful dose of this extensively studied regenerative peptide.* PeptiYouth® (S-Pea Oligopeptide-1 SP) PeptiYouth® is the world's first clinically tested anti-aging peptide discovered by artificial intelligence — identified within pea protein by the Nuritas Magnifier™ AI platform after scanning billions of plant-derived peptide sequences. It supports visible skin rejuvenation by activating endogenous collagen synthesis pathways, promoting elastin and fibrillin production, and targeting five measurable signs of aging simultaneously.* Clinical Evidence — 2 Double-Blind, Placebo-Controlled Human Trials* — Up to 26% reduction in wrinkle depth within 14 days (Canfield imaging technology)* — 22.4% reduction in pore size within 14 days* — 55% increase in collagen expression (ELISA mechanistic data)* — 56% increase in elastin expression* — 33% increase in fibrillin expression* — Synergistic effect demonstrated with retinol after 4 days (ex vivo)* — Published: International Journal of Cosmetic Science* Acetyl Hexapeptide-8 & Pentapeptide-18 Acetyl Hexapeptide-8 is a biomimetic peptide fragment of SNAP-25 that helps modulate SNARE complex assembly — the mechanism governing neurotransmitter release and muscle contraction signals at the neuromuscular junction.* Pentapeptide-18 works via a complementary and synergistic pathway, also supporting healthy neuromuscular signaling. When combined, these two neuropeptides demonstrate a synergistic wrinkle-supporting effect greater than either ingredient alone. BPC-ARG A stabilized peptide complex incorporated to support skin integrity, recovery pathways, and overall tissue resilience. Hyaluronic Acid Hyaluronic acid is a naturally occurring glycosaminoglycan that supports the extracellular matrix, helping maintain skin hydration, barrier function, and overall texture.* In combination with GHK-Cu, hyaluronic acid has been shown to support types I, IV, and VII collagen — important for both dermal integrity and basement membrane health. In FACEgevity™, it serves as the hydration foundation for the multi-peptide system, supporting moisture retention and barrier resilience while enhancing the delivery environment for the active peptides. Suggestions on how to use FACEgevity™ For optimal results, apply consistently as part of a daily skincare protocol. Clinical evidence for PeptiYouth® shows measurable results beginning within 14 days of twice-daily application.* Step 01 — Cleanse Apply to freshly cleansed, dry skin. Remove all surface debris and prior product to maximize peptide contact with the skin surface. Step 2 — Dispense 1 pump to the face and neck using upward, gentle strokes. Focus on areas of concern: forehead, periorbital area, nasolabial folds. Repeat a second time daily, if desired. Step 3 — Layer Apply before SPF in the morning. In the evening, apply after any water-based serums and before occlusive moisturizers. FACEgevity™ is the active peptide layer — position it to maximize absorption. Airless Pump Instructions Your product is packaged in a premium airless dispenser to help protect the formula from air exposure, supporting optimal freshness and performance with every use. To Prime Your Pump Firmly tap the bottom of the bottle on a hard surface 3–5 times. Cover the dispenser opening with your finger and pump continuously until the product begins dispensing. Initial priming may require several pumps, especially with thicker formulations. Please Note For best performance, do not remove the pump or nozzle. Doing so can introduce air into the system and require the dispenser to be re-primed. If you continue experiencing difficulty after priming, please contact Healthgevity Customer Support. We're happy to assist.
