Struggling with allergies, skin flare-ups or food sensitivities? HistaQuel by Researched Nutritionals helps regulate histamine levels and supports a calm immune response. With natural flavonoids and herbal extracts, it’s ideal for tackling seasonal allergies, histamine intolerance, or general inflammation — without the drowsiness of antihistamines. Allergies may develop as a result of many environmental conditions. When exposed to an allergen, the human body produces a natural mast cell activation response. This mast cell activation causes a release of histamine which when released, binds to histamine receptors causing common allergy symptoms. Histaquel combines seven flavonoids shown to support healthy mast cell function by promoting a healthy amount of histamine release, along with herbs shown to block histamine from attaching to receptors via competitive inhibition. Mast Cell Secure features a targeted flavonoid blend that supports healthy mast cell histamine release and regulates T cell interactions, promoting balanced Th2 cytokine release (IL-4 and IL-5) and IgE-mediated histamine release. HistaCheck enhances histamine receptor binding through competitive inhibition, supporting the immune response to allergens, and includes a highly bioavailable form of Quercetin, offering 20 times greater absorption than standard Quercetin. Order 3 and receive 3% discount with code HISTA3