✦ Verified product
HiXCap™ E1
USD 200.00
Grade
Amount/Package
Hongene Online Store
Verified independent store
→
.rte-hr { background: linear-gradient(to right, white, #162F65); border: 0; height: 1px; margin-top: 20px; } .rte-des-lists { display: flex; flex-wrap: wrap; gap: 25px; padding: 0
10px; margin-bottom: 25px; } .rte-list-card { flex: 1; background: rgba(239, 238, 236, 0.3); border-radius: 10px; padding: 20px; box-shadow: 0px 3px 10px rgba(22, 47, 101, 0.2); transition: transform 0.3s; min-width: 290px; position: relative; } .rte-list-card:hover { transform: translateY(-5px); } .rte-list-icon { width: 25px; height: 25px; margin: 0px 5px -5px 0px; fill: currentColor; } .rte-list-card h3 { font-size: 1.2em; padding-bottom: 8px; margin-bottom: 8px; color: #3361ac; } .rte-dashed-list-title { border-bottom: dashed rgba(193, 212, 231); } .rte-list-feature { border-left: solid 3px #3361ac; padding: 3px 0 3px 10px; margin: 0 5px 5px 0; } .rte-list-feature svg { width: 10px; height: 10px; margin-bottom: -5px; fill: #3361ac; } .rte-cite cite { display: block; margin-bottom: 8px; } .feature-single { display: block; padding: 10px; max-width: 300px; border: dashed 2px #c1d4e7; border-radius: 8px; box-shadow: 0 0 5px 1px rgba(22, 47, 101, 0.2); } HiXCap™ E1 is a chemically modified cap analogue that is incorporated into mRNA through co-transcription to ensure that the 5' end of the mRNA forms the correct cap structure, which is a necessary condition for ribosome recognition and translation initiation. Its molecular formula is m7G(5')pppA(2'O-Et)pG. Download HiXCap™ Brochure for more technical details. Applications Significantly enhance the translation efficiency of mRNA. It can resist degradation by nucleases, prolong the half-life and stability of mRNA within the cell, thereby increasing the protein expression level. The research data indicate that mRNA containing the HiXCapTM designs can improve translation under conditions of immune stress. Features and Benefits High capping efficiency Minimized GTP competition Improved translation efficiency Resistance to decapping enzymes Compatibility with delivery systems Scalable one-post synthesis and cost-effectiveness Enhanced immune evasion