Human Complement C4 Deficient Serum Catalog number: B2015111 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 1 mL Molecular Weight or Concentration: N/A Supplied as: Serum Applications: molecular tool for various biochemical applications Storage: -20° C Keywords: Complement Component 4, Complement Component IV, C4, CIV, Acidic C4 Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Monach PA. Complement Arthritis Rheumatol. 2024 Jan;76(1):1-8. Spycher MO, Spycher-Burger M, Späth PJ, Burckhardt JJ. Human serum induced opsonization of immunoglobulin G-coated polystyrene microspheres with complement components C3 and C4 as measured by flow cytometry J Immunol Methods. 1991 Dec 15;145(1-2):83-92. Yang Y, Chung EK, Zhou B, Lhotta K, Hebert LA, Birmingham DJ, Rovin BH, Yu CY. The intricate role of complement component C4 in human systemic lupus erythematosus Curr Dir Autoimmun. 2004;7:98-132. Margery-Muir AA, Bundell C, Wetherall JD, Whidborne R, Martinez P, Groth DM. Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort Lupus. 2018 Sep;27(10):1687-1696. Yang X, Sun J, Gao Y, Tan A, Zhang H, Hu Y, Feng J, Qin X, Tao S, Chen Z, Kim ST, Peng T, Liao M, Lin X, Zhang Z, Tang M, Li L, Mo L, Liang Z, Shi D, Huang Z, Huang X, Liu M, Liu Q, Zhang S, Trent JM, Zheng SL, Xu J, Mo Z. Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects PLoS Genet. 2012 Sep;8(9):e1002916. Roos A, Bouwman LH, Munoz J, Zuiverloon T, Faber-Krol MC, Fallaux-van den Houten FC, Klar-Mohamad N, Hack CE, Tilanus MG, Daha MR. Functional characterization of the lectin pathway of complement in human serum Mol Immunol. 2003 Jan;39(11):655-68. Lim HW, Perez HD, Goldstein IM, Gigli I. Complement-derived chemotactic activity is generated in human serum containing uroporphyrin after irradiation with 405 nm light J Clin Invest. 1981 Apr;67(4):1072-7. Yu CY, Chung EK, Yang Y, Blanchong CA, Jacobsen N, Saxena K, Yang Z, Miller W, Varga L, Fust G. Dancing with complement C4 and the RP-C4-CYP21-TNX (RCCX) modules of the major histocompatibility complex Prog Nucleic Acid Res Mol Biol. 2003;75:217-92. Petersen BH, Graham JA, Brooks GF. Human deficiency of the eighth component of complement. The requirement of C8 for serum Neisseria gonorrhoeae bactericidal activity J Clin Invest. 1976 Feb;57(2):283-90.