Human Complement Factor D Deficient Serum Catalog number: B2015460 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 1 mL Molecular Weight or Concentration: N/A Supplied as: Serum Applications: a molecular tool for various biochemical applications Storage: -20°C Keywords: Adipsin, Adipsin/Complement Factor D, And, C3 Convertase Activator, CFAD, CFD, D Component of Complement, DF, FactorD, PFD, Properdin Factor D Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Langereis JD, van der Molen RG, de Kat Angelino C, Henriet SS, de Jonge MI, Joosten I, Simons A, Schuurs-Hoeijmakers JH, van Deuren M, van Aerde K, van der Flier M. Complement factor D haplodeficiency is associated with a reduced complement activation speed and diminished bacterial killing Clin Transl Immunology. 2021 Apr 3;10(4):e1256. Sjöholm AG, Selander B, Ostenson S, Holmström E, Söderström C. Normal human serum depleted of C1q, factor D and properdin: its use in studies of complement activation APMIS. 1991 Dec;99(12):1120-8. Dare A, Chen SY. Adipsin in the pathogenesis of cardiovascular diseases Vascul Pharmacol. 2023 Dec 17;154:107270. Wu X, Hutson I, Akk AM, Mascharak S, Pham CTN, Hourcade DE, Brown R, Atkinson JP, Harris CA. Contribution of Adipose-Derived Factor D/Adipsin to Complement Alternative Pathway Activation: Lessons from Lipodystrophy J Immunol. 2018 Apr 15;200(8):2786-2797. Menger M, Aston WP. Factor D of the alternative pathway of bovine complement: isolation and characterization Vet Immunol Immunopathol. 1984 Oct;7(3-4):325-36. Dani R, Oroszlán G, Martinusz R, Farkas B, Dobos B, Vadas E, Závodszky P, Gál P, Dobó J. Quantification of the zymogenicity and the substrate-induced activity enhancement of complement factor D Front Immunol. 2023 May 22;14:1197023. Biesma DH, Hannema AJ, van Velzen-Blad H, Mulder L, van Zwieten R, Kluijt I, Roos D. A family with complement factor D deficiency J Clin Invest. 2001 Jul;108(2):233-40. Cohen G, Haag-Weber M, Hörl WH. Immune dysfunction in uremia Kidney Int Suppl. 1997 Nov;62:S79-82. Hiemstra PS, Langeler E, Compier B, Keepers Y, Leijh PC, van den Barselaar MT, Overbosch D, Daha MR. Complete and partial deficiencies of complement factor D in a Dutch family J Clin Invest. 1989 Dec;84(6):1957-61.
