Cambridge University Press, 8/16/2007EAN 9780521827140, ISBN10: 0521827140Hardcover, 1408 pages, 28.4 x 23 x 6.3 cmLanguage: EnglishThis comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.Part I. IntroductionPart II. Basic Virology and Viral Gene Effects on Host Cell FunctionsPart II. Basic Virology and Viral Gene Effects on Host Cell FunctionsPart II. Basic Virology and Viral Gene Effects on Host Cell FunctionsPart III. Pathogenesis, Clinical Disease, Host Response, and EpidemiologyPart III. Pathogenesis, Clinical Disease, Host Response, and EpidemiologyPart III. Pathogenesis, Clinical Disease, Host Response, and EpidemiologyPart III. HHV- 6a, 6b and 7 Ann Arvin and Richard WhitleyPart III. Pathogenesis, Clinical Disease, Host Response, and EpidemiologyPart IV. Non-Human Primate Herpesviruses Ann Arvin, Patrick Moore and Richard WhitleyPart V. Subversion of Adaptive Immunity Richard Whitley and Ann ArvinPart VI. Antiviral Therapy Richard WhitleyPart VII. Vaccines and Immunotherapy Ann Arvin and Koichi YamanishiPart VIII. Herpes as Therapeutic Agents Richard Whitley and Bernard Roizman.
