Human Hsf1 Catalog number: B2016792 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 50 µg Molecular Weight or Concentration: 58.6 kDa Supplied as: Solution Applications: a molecular tool for various biochemical applications Storage: -80°C Keywords: Heat Shock Factor 1, Heat Shock Transcription Factor 1, HSTF1 Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Feser CJ, Williams JM, Lammers DT, Bingham JR, Eckert MJ, Tolar J, Osborn MJ. Engineering Human Cells Expressing CRISPR/Cas9-Synergistic Activation Mediators for Recombinant Protein Production Int J Mol Sci. 2023 May 9;24(10):8468. Rabindran SK, Giorgi G, Clos J, Wu C. Molecular cloning and expression of a human heat shock factor, HSF1 Proc Natl Acad Sci U S A. 1991 Aug 15;88(16):6906-10. Wang M, Hu J, Qu J, Huang H, Zhang J, Zhang J, Li H, Cui X, Zhang F, Hu MY, Li J, Hu Y. The Therapeutic Roles of Recombinant Hsp90α on Cornea Epithelial Injury Invest Ophthalmol Vis Sci. 2022 Feb 1;63(2):30. Jiang Q, Zhang Z, Hu Y, Ma Y. Function of Hsf1 in SV40 T‑antigen‑transformed HEK293T cells Mol Med Rep. 2014 Dec;10(6):3139-44. Ding XZ, Tsokos GC, Smallridge RC, Kiang JG. Heat shock gene-expression in HSP-70 and HSF1 gene-transfected human epidermoid A-431 cells Mol Cell Biochem. 1997 Feb;167(1-2):145-52. Polidano J, Vankadari N, Price JT, Wilce JA. Detailed protocol for optimised expression and purification of functional monomeric human Heat Shock Factor 1 Protein Expr Purif. 2020 Dec;176:105722. Liu PC, Thiele DJ. Modulation of human heat shock factor trimerization by the linker domain J Biol Chem. 1999 Jun 11;274(24):17219-25. Moreno R, Banerjee S, Jackson AW, Quinn J, Baillie G, Dixon JE, Dinkova-Kostova AT, Edwards J, de la Vega L. The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress Cell Death Differ. 2021 May;28(5):1563-1578. Zhang N, Wu Y, Lyu X, Li B, Yan X, Xiong H, Li X, Huang G, Zeng Y, Zhang Y, Lian J, Ni Z, He F. HSF1 upregulates ATG4B expression and enhances epirubicin-induced protective autophagy in hepatocellular carcinoma cells Cancer Lett. 2017 Nov 28;409:81-90.
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