Hypothyroidism: Advances in Understanding and Management, edited by Rudolf Hoermann and Johannes W. Dietrich, presents a transformative approach to understanding the hypothalamic-pituitary-thyroid (HPT) axis and thyroid homeostasis. This book challenges conventional treatment paradigms, particularly for patients with persistent symptoms despite standard levothyroxine therapy, offering clinicians and researchers a comprehensive framework for diagnosis and management. It integrates the latest scientific advances with practical clinical guidance, highlighting the physiological and molecular mechanisms underlying hypothyroidism. Key Features Comprehensive coverage: Explores hypothyroidism from definition, pathophysiology, and patient presentation to endocrine regulation and treatment strategies HPT axis insights: Details thyroid hormone signaling, iodine metabolism, and the intricacies of hypothalamic-pituitary-thyroid homeostasis Paradigm shift in treatment: Examines why many patients do not respond to standard therapies and proposes innovative approaches to improve outcomes Evidence-based guidance: Integrates recent research into practical diagnostic and therapeutic strategies for clinicians Interdisciplinary appeal: Suitable for endocrinologists, general practitioners, researchers, and clinicians seeking in-depth understanding of thyroid regulation Educational utility: Aligns with curricula for aspiring endocrinologists and provides a valuable reference for informed patients Expert contributions: Chapters authored by leading specialists synthesize cutting-edge research with actionable clinical insights Product Details Publisher : Springer Publication date : 27 May 2025 Language : English ISBN-10 : 9819636817 ISBN-13 : 978-9819636815