Over the past decade, there has been an explosive development of research of intrinsically disordered proteins (IDPs), which are also known as unfolded proteins. Structural biologists now recognize that the functional diversity provided by disordered regions complements the functional repertoire of ordered protein regions.InIntrinsically Disordered ProteinAnalysis :Methods and Experimental Tools,expert researchers explorethe high abundance of IDPs in various organisms, their unique structural features, numerous functions, and crucial associations with different diseases.Volume 1includes sections on assessing IDPs in the living cell,NMR based techniques, vibrational spectroscopy, and other spectroscopic techniques. Written in the highly successfulMethods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.Thorough and intuitive,Intrinsically Disordered ProteinAnalysis: Methods and Experimental Toolshelps scientists further their investigations of these fascinating and dynamic molecules.
