Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in all living cells and plays a crucial role in cellular health. Within the mitochondria, NAD+ fuels processes that support DNA integrity and cellular repair mechanisms. Research suggests that NAD+ may help maintain telomere length, the protective caps at the ends of chromosomes that shorten with age, by activating sirtuins like SIRT1. Additionally, NAD+ activates PARP1, a protein essential for DNA repair, potentially contributing to a slower rate of aging. How often should I get NAD IVs The frequency of the infusions are customized to the individual and their primary concerns. Typical dosing would be a series of 3-7 IVs done daily or every other day to quickly boost up the body’s NAD stores. As maintenance treatment, some people may only need NAD treatment a couple times a year.