Sea jellies, or jellyfish, are invertebrate plankton that have been drifting around the vast oceans for over 500 million years. They are composed of 92 to 95% water and breathe only through their skin. They lack a heart, brain, bones, or head. One species called Turritopsis dohrnii is biologically immortal and resides in the Mediterranean Sea and off the coast of Japan. Edible jellyfish contain a large amount of collagen in their mesoglea, a gelatinous layer between the internal and external layers of their body structure. The amino acids found within collagen support human brain cells and protect against photoaging and skin damage from excessive ultraviolet sunlight. They have also been studied to support the innate immune system by promoting cytokine production and phagocytosis activity of macrophages. Jellyfish collagen is the only collagen that contains all twenty essential and "non-essential" amino acids. This makes it a complete protein source. Amino acids regulate nearly every biochemical reaction in the body. One of the most fascinating benefits of consuming jellyfish collagen is its effects on the brain. Neurotransmitters, the chemical messengers that our brain uses, are made up of amino acids. Larger neurotransmitters are multiple amino acids bound together which form neuropeptides like endorphins that elevate our mood. It also contains minerals that support overall brain function including potassium, sodium, phosphorus, chloride, copper, calcium, magnesium, manganese, zinc, iron, sulfur and silicon. It has calcium binding proteins which may help prevent neuronal damage and cognitive decline. The amino acids most abundant in Jellyfish Jolt are glutamic acid, serine, and tryptophan. These three play a crucial role in regulating the gut-brain-immune axis and are building blocks for serotonin, the gut barrier, and the enteric and central nervous system. The benefits of jellyfish collagen are tremendous. "Jellyfish collagen has also been referred to as collagen type 0 due to its similarity to multiple collagen types..." (Ahmed, et al 2021). It holds up to 200% more water than other collagens on the market. Jellyfish Jolt is truly in a league of its own. SUGGESTED USAGE: One or more capsules everyday with or without a meal. RESEARCH: Jellyfish Collagen Stimulates Production of TNF-a and IL-6 by J774.1 Cells Through Activation of NF-kB and JNK via TLR4 Signaling Pathway. Molecular Immunology. Volume 58, Issue 1, March 2014, Pages 32-37. Marine Collagen Substrates for 2D and 3D Ovarian Cancer Cell Systems. Frontiers in Bioengineering and Biotechnology, 13 December 2019. Barrel Jellyfish (Rhizostoma pulmo) as Source of Antioxidant Peptides. Marine Drugs. 2019 Feb; 17(2): 134. Effects of Collagen and Collagen Hydrolysate from Jellyfish Umbrella on Histological and Immunity Changes of Mice Photoaging. Nutrients 5(1):223-33, January 2013. Study on Effect of Jellyfish Collagen Hydrolysate on Anti-fatigue and Anti-oxidation. Food Hydrocolloids 25(5):1350-1353, July 2011. Extraction of Collagen from Jellyfish (Rhopilema esculentum) and Wound Healing-Promoting Effect in Mouse. Food Science, 2010. Effects of Collagen Peptide from Cyanea nozakii on Mouse Immune Function. Agricultural Science and Technology, 2009. Isolation, Characterization and Biological Evaluation of Jellyfish Collagen for Use in Biomedical Applications. Marine Drugs. 2011; 9(6): 967–983. June 2011.
