Premier Research Labs Premier Joint & Disc Healthy Joint and Disc Support with Minor Pain Relief Ingredients Serving Size: 3 capsules Amount Per Serving ParActin® (Organic Andrographis paniculata (leaf) Extract) 300 mg Andrographolide 150 mg White Willow (bark) Extract (Salix alba) 124 mg Salicin 120 mg Sodium Hyaluronate (from Streptococcus zooepidemicus Fermentation) 540mg Hyaluronic Acid 48 mg Other Ingredients: Organic Rice Concentrate, Plant-Source Capsules (cellulose, water), Organic Rice Bran Suggested Use Take 3 capsules daily or as directed by a health professional. More Info Premier Joint & Disc is a premier nature-based botanical formula, clinically formulated to support a healthy inflammatory response and minor pain relief from normal day to day joint wear and tear, specific to: Joint mobility Disc health Healthy cartilage Sports recovery / muscle function Premier Joint & Disc is scientifically formulated to deliver an aggressive panel of clinically reviewed ingredients that contain powerful phytochemical compounds designed to directly promote a healthy inflammatory response by targeting key chemical signaling pathways that have the capacity to modulate pro-inflammatory cytokines and proteins associated with minor pain from everyday activities. This triple strength formula is tailored with three clinically reviewed ingredients designed to provide long-term support of the joints, discs, and musculoskeletal systems of the body. Leading the list of this trifecta is the distinguished, centuries-old Andrographis paniculata, patented as ParActin™. This revered botanical continues to be regarded by health professionals worldwide as one of nature’s superstars providing reliable results to their clients who need immediate joint support. Complementing this notable ingredient is the well-researched White Willow (bark) Extract, which provides the highly effective compound, salicin. Lastly, anchoring the trio is Sodium Hyaluronate which is well known for its active constituent, hyaluronic acid. Andrographis paniculata, an annual herbaceous plant in the family Acanthaceae, is one of the most commonly used medicinal plants in the traditional systems of Traditional Chinese and Ayurvedic medicine. It continues to be widely cultivated in India, China, and Southeastern Asia. Known as the “King of Bitters,” its bioactive components called andrographolides have been extensively tested and have demonstrated their ability to promote modulatory activity at multiple points in the chemical signaling pathway of the inflammatory response systems of the body. Salicin is a natural compound derived from the bark of the White Willow Tree. The use of White Willow Bark dates back to the early origins of medicine when Hippocrates first documented its efficacy in supporting the body during episodes of minor aches and pains. Optimal levels of synovial fluid in joint cavities are essential to maintaining healthy joints and mobility. Synovial fluid is the “viscous fluid” that supports the integrity of joints by shuttling in nutrients and keeping the cartilage hydrated and healthy. Synovial fluid contains high levels of hyaluronic acid (HA) in its membrane to promote its fluid viscosity and is critical to preserving the normal cartilaginous matrix. HA is a naturally occurring polymer found in all joints, discs, connective tissue, tendons, bones, and cartilage (especially the hyaline cartilage, which covers the ends of bones to provide cushioning).
