This blend of natural ingredients has been formulated to assist with joint support and flexibility. Containing 1500 mg of Glucosamine which helps keep cartilage in joints healthy. Chondroitin helps with joint mobility and flexibility.* Formula Purposes & Benefits Joint flex is a world-class formula that supports healthy joints, reduced inflammation, reduced allergies, reduced joint pain, joint flexibility, reduced muscle damage from exercise, and increased exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with optimal ratios of collagen peptides to produce world class results. Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards. Formula Ingredient Deck Benefits Of Each Ingredient Ginger Supports immune health, reduced blood pressure, digestive health, blood sugar regulation, and sexual health in men (110). Supports immune health via enhanced antioxidant, antimicrobial, and anti-inflammatory properties (110). Supports sex hormone health via decreased oxidative stress, increased luteinizing hormone (LH) production, reduced oxidative stress, reduced lipid peroxidation, enhanced activity antioxidant enzymes, increased blood flow, and recycling of testosterone receptors (110). Glucosamine Supports connective tissue health and decreased joint stiffness (111). Glucosamine and chondroitin sulfate have showed beneficial effects on joint tissues in osteoarthritis (OA) (111). Quercetin Supports antioxidant, anti-inflammatory, immune system defense, reduced homocysteine (allergies), reduced triglycerides and combats bacterial infections (114,115,116). Supports immune health via reduced c-reactive protein (major inflammatory biomarker), increased neutrophil chemotaxis, macrophage phagocytosis, NK cell lytic activity and mitogen-stimulated lymphocyte (white blood cell) proliferation (114). Supports antiviral and antibacterial activity in influenza A strains H1N1 (114). Turmeric Supports antioxidant, cardio-protective, anti-inflammatory, anti-microbial, nephro-protective, hepatoprotective, immunomodulatory, and anti-rheumatic effects (123). Reduces inflammation via decreases of inflammatory markers such as c-reactive protein, interleukin 6, tumor necrosis factor, and decreased cytokine production (123). Supports joint health via decreases in connective tissue inflammation and improved pain in individuals with osteoarthritis (122). Supports blood sugar regulation via increased pancreatic beta cell function and improved insulin sensitivity (121). Methionine Reduces inflammation and increases energy production via increased creatine synthesis (112). Chondroitin Supports connective tissue health and decreased joint stiffness (111). Glucosamine and chondroitin sulfate have shown beneficial effects on joint tissues in osteoarthritis (OA) (111). Boswellia Supports immune health, joint health, joint pain, and healthy inflammation levels (117,124, 125). Reduces inflammation via decreases in c-reactive protein, decreased arthritis in osteoarthritic patients, and reduced joint stiffness (124). Extracts of Boswellia have suppressed inflammation via local tissue tumor necrosis factor-α (TNFα) and interleukin-1β (IL-1β) (125). Bromelain The enzyme that supports digestive health, joint, health, immune health, and combats arthritis, inflammation, indigestion, and pancreatic insufficiency. Proper Use of This Supplement Suggested Use: For best results, take three (3) capsules daily before a meal. For quicker relief, take a loading dose of six capsules daily for the first two weeks. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. High-quality joint support in a powerful and efficaciously dosed formula. 2. Uses cheap sources of toxic herbs that contain high amounts of fillers and heavy metals. Sources Hasani, H., Arab, A., Hadi, A., Pourmasoumi, M., Ghavami, A., & Miraghajani, M. (2019). Does ginger supplementation lower blood pressure? A systematic review and meta-analysis of clinical trials. Phytotherapy research : PTR, 33(6), 1639–1647. https://doi.org/10.1002/ptr.6362 Simental-Mendía, M., Sánchez-García, A., Vilchez-Cavazos, F., Acosta-Olivo, C. A., Peña-Martínez, V. M., & Simental-Mendía, L. E. (2018). Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials. Rheumatology international, 38(8), 1413–1428. https://doi.org/10.1007/s00296-018-4077-2 Tripodi, F., Badone, B., Vescovi, M., Milanesi, R., Nonnis, S., Maffioli, E., Bonanomi, M., Gaglio, D., Tedeschi, G., & Coccetti, P. (2020). Methionine Supplementation Affects Metabolism and Reduces Tumor Aggressiveness in Liver Cancer Cells. Cells, 9(11), 2491. https://doi.org/10.3390/cells9112491 Sahebkar A. (2017). Effects of quercetin supplementation on lipid profile: A systematic review and meta-analysis of randomized controlled trials. Critical reviews in food science and nutrition, 57(4), 666–676. https://doi.org/10.1080/10408398.2014.948609 Mohammadi-Sartang, M., Mazloom, Z., Sherafatmanesh, S., Ghorbani, M., & Firoozi, D. (2017). Effects of supplementation with quercetin on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials. European journal of clinical nutrition, 71(9), 1033–1039. https://doi.org/10.1038/ejcn.2017.55 Sahebkar A. (2017). Effects of quercetin supplementation on lipid profile: A systematic review and meta-analysis of randomized controlled trials. Critical reviews in food science and nutrition, 57(4), 666–676. https://doi.org/10.1080/10408398.2014.948609 Chilelli, N. C., Ragazzi, E., Valentini, R., Cosma, C., Ferraresso, S., Lapolla, A., & Sartore, G. (2016). Curcumin and Boswellia serrata Modulate the Glyco-Oxidative Status and Lipo-Oxidation in Master Athletes. Nutrients, 8(11), 745. https://doi.org/10.3390/nu8110745 Mata, I., Mata, S., Menezes, R., Faccioli, L. S., Bandeira, K. K., & Bosco, S. (2020). Benefits of turmeric supplementation for skin health in chronic diseases: a systematic review. Critical reviews in food science and nutrition, 1–15. Advance online publication. https://doi.org/10.1080/10408398.2020.1798353 Majeed, M., Majeed, S., Narayanan, N. K., & Nagabhushanam, K. (2019). A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee. Phytotherapy research : PTR, 33(5), 1457–1468. https://doi.org/10.1002/ptr.6338 Umar, S., Umar, K., Sarwar, A. H., Khan, A., Ahmad, N., Ahmad, S., Katiyar, C. K., Husain, S. A., & Khan, H. A. (2014). Boswellia serrata extract attenuates inflammatory mediators and oxidative stress in collagen induced arthritis. Phytomedicine : international journal of phytotherapy and phytopharmacology, 21(6), 847–856. https://doi.org/10.1016/j.phymed.2014.02.001 Serving Size: 3 Capsules;Capsules Per Container: 60;Bottle Color: White;Bottle Size: 175cc;Lid Color: White * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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