NeuroScience Kavinace OS .embed-container { position: relative; padding-bottom: 56.25%; height: 0; overflow: hidden; max-width: 100%; } .embed-container iframe, .embed-container object, .embed-container embed { position: absolute; top: 0; left: 0; width: 100%; height: 100%; } Ingredients to target complete cellular health for bringing occasional sleeplessness into balance, in a formula reported to benefit both healthy sleep onset and optimal sleep efficiency. Patient Profile: Requires quick relief from sleeplessness Needs help falling asleep Unhealthy lifestyle habits Known or suspected immune activity The Science: The nervous system works with the immune system to regulate the sleep-wake cycle and the immune response During daytime activity, the immune system generates free radicals and depletes antioxidants During bedtime hours, accumulated free radicals can stimulate the immune system, with the adaptive immune system at its most active Poor sleep has been shown to increase oxidative stress markers, perpetuating the Immune-Sleep Cycle For more information, check out our blog post - NeuroScience For Winning at Brain Health Ingredients Serving Size: 2 Capsules Amount/Serving Magnesium (as magnesium bisglycinate chelate) 25 mg Zinc (as zinc bisglycinate chelate) 15 mg Selenium (as selenomethionine) 200 mcg Melatonin 5 mg Proprietary Blend: 214 mg L-theanine, Trans-resveratrol (Polygonum cuspidatum)(root), and Astaxanthin (Haematococcus pluvialis) Other Ingredients: Vegetable capsule (hypromellose, water), organic rice concentrate, microcrystalline cellulose, dicalcium phosphate, citric acid, and glycine. Suggested Use Take 2 capsules at bedtime or as directed by your healthcare provider. Warning: If you are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children. Storage: This product has a tamper-evident seal under the cap. Do not use if the seal is broken or missing. Store at room temperature, in a dry place. More Info. One night of poor sleep changes cellular metabolic function Metabolic changes worsen the Immune-Sleep Cycle, perpetuating more sleepless nights Decreased antioxidant capacity increases susceptibility to negative effects of free radicals and oxidative stress Oxidative stress modulates immune regulators like Nf-kB Wake promoting substances (hormones and neurotransmitters) respond to immune activation and further disrupt sleep The uniquely formulated blend of Kavinace OS comprehensively intervenes at every portion of the Immune-Sleep Cycle Researched ingredient blend, proven results Study participants were prescreened for poor sleep (PSQI), received one serving of Kavinace OS at bedtime for seven days, and submitted a daily sleep diary Fall asleep quickly. Extremely significant reductions in sleep latency were reported after the first dose of Kavinace OS, with ongoing improvement through day four Sleep better. Significant improvement in sleep efficiency, or total sleep time relative to time in bed, was reported after one dose of Kavinace OS Kavinace OS provides quick relief from sleeplessness at the symptom and cellular level