L-Lactate for Interference Testing Catalog number: B2010200 Lot number: Batch Dependent Expiration Date: Batch dependent Volume/Weight: 1 mL 100 mg/mL pH: na Supplied as: Ready-to-use Appearance: Solution Applications: highly concentrated solution of Lactate (L-Lactate) (100 mg/mL) provided with the corresponding diluent. Solution can be spiked in specimen to test Lactate (L-Lactate) interference in various assays. Storage: -20C Keywords: (S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um. L-Lactate for Interference Testing is a biotechnology-grade reagent designed to simulate endogenous lactate interference in clinical assay validation workflows. Supplied as a highly concentrated 100 mg/mL solution, this ready-to-use reagent enables researchers to spike specimens with physiologically relevant levels of L-Lactate to evaluate assay robustness, specificity, and analytical accuracy. It is particularly useful in validating enzymatic assays, immunoassays, and biosensor platforms where lactate may impact signal detection or assay kinetics. Researchers in clinical chemistry, metabolic profiling, and diagnostic assay development rely on interference testing to meet CLSI EP07 guidelines and ensure reliable performance across diverse patient samples. This reagent is prepared with ultrapure water and filtered through 0.22 µm membranes to ensure high purity and minimal background interference. Supplied in a 1 mL format and stored at –20°C, it integrates seamlessly into manual and automated workflows. Whether you're developing a lactate-sensitive assay or troubleshooting unexpected signal variation, this reagent offers a precise and reproducible solution for interference evaluation. Key benefits: 100 mg/mL L-Lactate solution for interference simulation in clinical assays Supports EP07-compliant assay validation and robustness testing Ready-to-use format with corresponding diluent included Filtered through 0.22 µm membranes using ultrapure water Stored at –20°C for long-term stability and reproducibility Products are for in vitro research use only (RUO). References 1: Brooks GA. The Science and Translation of Lactat Shuttle Theory. Cell Metab.2018 Apr 3;27(4):757-785. 2: Vincent JL, Quintairos E Silva A, Couto L Jr, Taccone FS. The value of bloodlactate kinetics in critically ill patients: a systematic review. Crit Care.2016 Aug 13;20(1):257. 3: Lucertini F, Gervasi M, D’Amen G, Sisti D, Rocchi MBL, Stocchi V, Benelli P.Effect of water-based recovery on blood lactat removal after high-intensityexercise. PLoS One. 2017 Sep 6;12(9):e0184240. 4: Xu S, Jiang R, Mueller R, Hoesli N, Kretz T, Bowers J, Chen H. Probinglactat metabolism variations in large-scale bioreactors. Biotechnol Prog. 2018May;34(3):756-766. 5: Narwal V, Sharma M, Rani S, Pundir CS. An ultrasensitive amperometricdetermination of lactat by lactat dehydrogenase nanoparticles immobilized ontoAu electrode. Int J Biol Macromol. 2018 Aug;115:767-775. 6: Thomsen MT, Wang T, Milsom WK, Bayley M. Lactat provides a strong pH-independent ventilatory signal in the facultative air-breathing teleostPangasianodon hypophthalmus. Sci Rep. 2017 Jul 25;7(1):6378. 7: Nikolaidis S, Karpouzi C, Tsalis G, Kabasakalis A, Papaioannou KG, Mougios V.Reliability of urine lactate as a novel biomarker of lactate_production capacityin maximal swimming. Biomarkers. 2016;21(4):328-34. 8: Goers L, Ainsworth C, Goey CH, Kontoravdi C, Freemont PS, Polizzi KM. Whole-cell Escherichia coli lactate biosensor for monitoring mammalian cell culturesduring biopharmaceutical production. Biotechnol Bioeng. 2017Jun;114(6):1290-1300. 9: Shah NC, Lyandres O, Walsh JT Jr, Glucksberg MR, Van Duyne RP. Lactate_andsequential lactate-glucose sensing using surface-enhanced Raman spectroscopy.Anal Chem. 2007 Sep 15;79(18):6927-32. All Interference Products Brochure
