Product Details What is L-Methionine? Methionine is an essential amino acid and a precursor to several other amino acids, such as cysteine and taurine. It’s also a precursor to SAMe and the powerful antioxidant glutathione. One of methionine’s primary functions is to convert into sulfuric molecules and produce other sulfur-containing compounds. The body needs these sulfur-containing molecules for proper cell function and DNA synthesis. Methionine is also essential for protein synthesis, particularly after strenuous workouts that damage the muscles. Potential Methionine Benefits Methionine is one of the nine essential amino acids that the body needs to sustain life. However, humans can’t synthesize it and rely on dietary sources to meet their nutritional needs. Methionine is one of the most versatile amino acids. For example, it converts readily into s-adenosylmethionine (SAMe). SAMe helps synthesize creatine, which is critical for producing cellular energy. SAMe can also donate methyl groups to DNA and protein molecules. Methionine can also convert into carnitine, lecithin, and phosphatidylcholine. Methionine and Antioxidants Methionine performs a diverse array of functions in the body. However, the most important is its ability to produce other vital molecules, such as cysteine. From there, cysteine can produce taurine and glutathione. Glutathione is the most powerful antioxidant in the body and supports the natural immune system’s defenses against toxins and pathogens. It also boosts the levels of other antioxidants, enhances the body's resistance to oxidative stress, and reduces oxidative damage. Methionine and Detoxification Methionine assists with many detoxification processes due to its sulfur contents. It protects cells against pollutants and improves selenium and zinc bioavailability and uptake. Selenium and zinc work together to repair and protect DNA. Methionine is also a chelating agent that helps the body excrete heavy metals like mercury and lead by binding to them. It helps attenuate copper toxicity as well. It also has lipotropic properties that help prevent fat accumulation in the liver. Additionally, methionine is a known antidote to acetaminophen poisoning. Methionine for Hair, Skin, and Nail Health Methionine is the body’s primary sulfur supplier, which is critical for hair, skin, and nail health. Specifically, it improves skin tone, hair pliability, and nail strength. It also influences hair follicles and stimulates hair growth by regulating ammonia. Potential Methionine Side Effects Most individuals tolerate standard methionine doses with significant adverse effects. However, high doses may cause headaches, nausea, or vomiting. Excessive doses can cause more concerning side effects, such as changing serum pH and potassium levels, raising white blood cell count, and increasing calcium excretion. Methionine may increase homocysteine levels in individuals with B vitamin deficiencies, particularly vitamin B12. References https://academic.oup.com/jn/article/136/6/1636S/4664439 https://www.ncbi.nlm.nih.gov/pubmed/14988435 https://www.sciencedirect.com/science/article/pii/B9780124201941000270 https://www.ncbi.nlm.nih.gov/pubmed/24791918 https://academic.oup.com/jn/article/136/6/1636S/4664439 https://www.ncbi.nlm.nih.gov/pubmed/23180741 https://pubchem.ncbi.nlm.nih.gov/compound/Methionine https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C29600 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786808 http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16643 http://www.webmd.com/vitamins-supplements/ingredientmono-42-methionine.aspx?activeingredientid=42& https://www.drugbank.ca/drugs/DB00134 https://pubmed.ncbi.nlm.nih.gov/11053901 https://pubmed.ncbi.nlm.nih.gov/11053502 Tested by Accredited 3rd Party Labs PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here. *NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
