Food supplement in the form of a hard capsule containing lactoferrin - a protein from the glycoprotein group, that has the ability to bind and transport iron. Lactoferrin Proferrin® is obtained from cow’s milk. If you want to take care of your immunity and improve iron absorption, then consider lactoferrin supplementation [1]. Lactoferrin is described as a multifunctional protein that is found in many body fluids, including milk, saliva and tears [2]. It can help you protect against bacteria and viruses and support every cell in the body against oxidative stress [3]. Lactoferrin, which is part of milk proteins (lacto + ferrrin = milk + iron), has antiviral, antimicrobial, antioxidant and immunomodulatory effects [4]. It is an iron-binding glycoprotein (approximately 77 kDa) that helps to balance iron levels in the body. Iron deficiency manifested by excessive fatigue, weakness, dizziness and headaches, palpitations, as well as excessive hair loss and deterioration of skin and nails significantly worsens the quality of life [5]. Lactoferrin supplementation in such cases may be beneficial in supporting iron absorption and iron deficiency [6]. Excess iron can also be harmful leading to the formation of reactive oxygen species (ROS), and lactoferrin, due to its ability to strongly and reversibly bind iron ions, assists the body in maintaining homeostasis of this element [3]. This glycoprotein supports the immune system in dealing with chronic inflammatory processes leading to iron deficiency [7]. In a study involving female long-distance runners who supplemented with lactoferrin in combination with iron for 8 weeks, they saw beneficial changes in blood counts and lactate levels compared to participants who only received iron [8]. This suggests a positive effect of lactoferrin on iron levels and exercise tolerance in physically active individuals. Furthermore, lactoferrin can be successfully used by pregnant women not only in supporting iron absorption, but also in supporting immune function due to its proven safety. The review noted that, under the influence of lactoferrin supplementation, pregnant women show improved iron absorption, favourable changes in blood morphology and less digestive discomfort with concomitant oral iron intake [6]. The reduced gastrointestinal side effects when combining oral iron with lactoferrin is most likely due to the lack of excess free iron available in the gastrointestinal tract. This avoids mucosal irritation and impaired intestinal motility [9]. In addition, lactoferrin may support our immune function by increasing immune cell activity and inhibiting pathogenic bacteria and viruses [4]. Observations have shown a positive effect of lactoferrin supplementation or consumption of lactoferrin-enriched fermented milk on the skin by reducing acne vulgaris by 20.3%compared to placebo and improving its condition overall [10,11]. Our supplement contains up to 200 mg of Proferrin® lactoferrin, the purest branded lactoferrin available on the market (>95%), in 1 capsule. It is extracted from cow's milk, of high quality, from controlled farms. It is processed by microfiltration (without pasteurisation) and low-temperature drying, resulting in a native lactoferrin, with a structure and bioactivity identical to that found in fresh milk. Lactoferrin has the ability to bind and transport iron, so if you are looking to improve iron absorption - choose our high lactoferrin supplement! Why would someone benefit from supplementing with Lactoferrin, 200 mg?- High content of lactoferrin.- Lactoferrin has the ability to bind and transport iron.What is special about capsules Lactoferrin, 200 mg?- Contains Proferrin®, the purest branded lactoferrin available on the market (95%).- 200 mg of Proferrin® in one capsule.- Lactoferrin processed by microfiltration (without pasteurisation) and low-temperature drying.- Clean label - no unnecessary additives.- Suitable for vegetarians.- Sugar-free, gluten-free, soy-free, GMO-free.- Packaging made of BioPET (30% of the plastic comes from sugar cane).[1] Berthon, B. S. et al. (2022). Effect of Lactoferrin Supplementation on Inflammation, Immune Function, and Prevention of Respiratory Tract Infections in Humans: A Systematic Review and Meta-analysis. Advances in nutrition (Bethesda, Md.), 13(5), 1799–1819. https://doi.org/10.1093/advances/nmac047 [2] Gawel, P., & Krolak-Olejnik, B. (2023). Lactoferrin supplementation during pregnancy - a review of the literature and current recommendations. Ginekologia polska, 10.5603/GP.a2023.0020. Advance online publication. https://doi.org/10.5603/GP.a2023.0020 [3] Kowalczyk, P. et al. (2022). The Lactoferrin Phenomenon-A Miracle Molecule. Molecules (Basel, Switzerland), 27(9), 2941. https://doi.org/10.3390/molecules27092941 [4] Berthon, B. S. et al. (2022). Effect of Lactoferrin Supplementation on Inflammation, Immune Function, and Prevention of Respiratory Tract Infections in Humans: A Systematic Review and Meta-analysis. Advances in nutrition (Bethesda, Md.), 13(5), 1799–1819. https://doi.org/10.1093/advances/nmac047 [5] Freeman, A. M., Rai, M., & Morando, D. W. (2023). Anemia Screening. In StatPearls. StatPearls Publishing. [6] Gawel, P., & Krolak-Olejnik, B. (2023). Lactoferrin supplementation during pregnancy - a review of the literature and current recommendations. Ginekologia polska, 10.5603/GP.a2023.0020. Advance online publication. https://doi.org/10.5603/GP.a2023.0020[7] Artym, J., Zimecki, M., & Kruzel, M. L. (2021). Lactoferrin for Prevention and Treatment of Anemia and Inflammation in Pregnant Women: A Comprehensive Review. Biomedicines, 9(8), 898. https://doi.org/10.3390/biomedicines9080898[8] Koikawa, N. et al. (2008). Preventive effect of lactoferrin intake on anemia in female long distance runners. Bioscience, biotechnology, and biochemistry, 72(4), 931–935. https://doi.org/10.1271/bbb.70383 [9] Reda, R. et al. (2022). Effect of Lactoferrin Supplementation on Serum Iron level and Haematological Parameters after Sleeve Gastrectomy. Afro-Egyptian Journal of Infectious and Endemic Diseases, 12(4), 358-366. doi: 10.21608/aeji.2022.160975.1250 [10] Mueller, E. A. et al. (2011). Efficacy and tolerability of oral lactoferrin supplementation in mild to moderate acne vulgaris: an exploratory study. Current medical research and opinion, 27(4), 793–797. https://doi.org/10.1185/03007995.2011.557720 [11] Kim, J. et al. (2010). Dietary effect of lactoferrin-enriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris. Nutrition (Burbank, Los Angeles County, Calif.), 26(9), 902–909. https://doi.org/10.1016/j.nut.2010.05.011
