Pure Encapsulations Ligament Restore Helps Maintain Healthy Tendons, Ligaments, and Joints Glucosamine is required for the synthesis of proteoglycans, the molecules responsible for providing tendons, ligaments, and cartilage their resiliency and strength. It also helps protect cartilage from the effects of mechanical stress. Sulfate, another component of proteoglycans, works synergistically with glucosamine to enhance cartilage repair and regeneration. BioCell Collagen® provides hydrolyzed and denatured low molecular weight collagen. Additionally, it provides a naturally occurring blend of hyaluronic acid (HA), chondroitin sulfate, glucosamine sulfate, and amino acids to promote cartilage synthesis and joint integrity. Key Benefits and Features: Ages 18 and up Ligament function and comfort Supports collagen formation for healthy tendons, ligaments, and joints Helps support normal recovery from exercise Blend of glucosamine, collagen, amino acids, and herbal extracts Ingredients Serving Size: 2 Vegetarian Capsules Amount/Serving Vitamin C (as ascorbic acid) 100 mg Glucosamine sulfate (from crab and shrimp) 750 mg BioCell Collagen hydrolyzed collagen complex (from chicken sternal cartilage) 200 mg providing (typical): hydrolyzed collagen 60% 120 mg L-Proline (free-form) 250 mg L-Lysine HCI (free-form) 250 mg Silica (from bamboo) 7.5 mg Devil's claw (Harpagophytum procumbens and Harpagophytum zeyheri) extract (root) (standardized to contain 5% harpagosides) 50 mg Turmeric (Curcuma longa) extract (root) (standardized to contain 95% curcuminoids) 50 mg Other Ingredients: Vegetarian capsule (cellulose, water), and ascorbyl palmitate. Contains: Shellfish (crab and shrimp). Does Not Contain: Wheat, soy, dairy, eggs, artificial colors, artificial sweeteners, coatings, shellacs, GMOs, tree nuts, peanuts, sesame, unnecessary binders, fillers, preservatives, magnesium stearate, gluten, trans fat, and hydrogenated oils. Gluten Free, Non-GMO Suggested Use As a dietary supplement, take 2 capsules, 2 times daily, with 8-10 oz of water, with meals. Warning: If you are pregnant or lactating, have any health conditions, or are taking any medication, consult your health professional before use. Do not take if you are sensitive to shellfish. Storage: Refrigerate after opening. More Info. A double-blind, placebo-controlled study involving 16 individuals supplementing with BioCell Collagen® for eight weeks indicated statistically significant support for joint function and comfort. To further encourage collagen formation, this formula is enhanced with l-lysine and l-proline. These amino acids are hydroxylated to form hydroxyproline and hydroxylysine in a reaction involving vitamin C, forming the “glue” that holds collagen together. In the body, silica is found primarily in connective tissue and plays a role in collagen tissue formation. Devil’s claw and curcumin are included to support joint flexibility, function, and comfort, in part by maintaining healthy eicosanoid metabolism.5 Glucosamine sulfate is derived from crab and shrimp Hydrolyzed collagen complex is derived from chicken sternal cartilage and typically provides 60% hydrolyzed collagen, 20% chondroitin sulfate, and 10% hyaluronic acid l-proline and l-lysine are derived from fermentation Ascorbic acid is derived from corn dextrose fermentation Silica is from bamboo extract, which is derived from the stem of the botanical Bambusa vulgaris Curcumin (turmeric) is derived from Curcuma longa and standardized to contain 95% curcuminoids Devil’s claw is derived from Harpagophytum procumbens and standardized to contain 5% harpagosides Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil Hypoallergenic plant fiber is derived from pine cellulose