Pure Encapsulations Lithium (Orotate) 5mg Supports Emotional Wellness, Mood, and Behavior Offers the essential trace element lithium to support healthy mental function, including mood, emotion, memory, and behavior. Lithium is an essential micronutrient with some chemical properties similar to calcium and magnesium. It is present in all organs and tissues in the body. Lithium has a long history of clinical use for supporting healthy mood and behavior, possibly through dopamine- and serotonin- mediated mechanisms. Lithium supports neurotransmitter systems and signaling cascades involved in brain health and behavior. Key Benefits and Features: Ages 18 and up Emotional wellness and mood support Supports mood, emotional wellness, and behavioral health Supports cognitive function Promotes neurotransmitter activity Combination of lithium and N-acetyl-l-cysteine (NAC) Part of the PureSYNAPSETM product line Made with high-quality ingredients backed by verifiable science Ingredients Serving Size: 1 Vegetarian Capsule Amount/Serving Lithium (as lithium orotate) 5 mg N-Acetyl-L-Cysteine (free-form) 200 mg Other Ingredients: Vegetarian capsule (cellulose, water), ascorbyl palmitate, and hypoallergenic plant fiber (cellulose). Does Not Contain: Wheat, soy, dairy, eggs, artificial colors, artificial sweeteners, coatings, shellacs, GMOs, tree nuts, peanuts, sesame, unnecessary binders, fillers, preservatives, magnesium stearate, gluten, trans fat, and hydrogenated oils. Gluten Free, Non-GMO, Hypoallergenic Suggested Use As a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional. Warning: Not to be taken by pregnant and lactating women. Consult your health professional before using this product. Not to be taken in conjunction with antidepressants unless advised by a health professional. Individuals with bipolar disorder and depression must be monitored closely by a health professional if taking this supplement. It is recommended that individuals taking this supplement have lithium levels and kidney function monitored regularly. Do not exceed the dose recommended by your health professional. their Storage: Store in a cool, dry place. More Info. Several studies suggest that lithium supports memory and mood. A 12-month, randomized, double-blind trial involving 45 individuals suggests that low-dose lithium supplementation promotes cognitive performance. In cultured neurons, lithium enhances gene expression of glutathione-S-transferase (GST), a detoxification enzyme with neuroprotective functions. Lithium has also been shown to promote healthy brain-derived neurotrophic factor (BDNF) levels in animal models and humans. Lithium is mined and refined Orotate and N-acetyl-l-cysteine are synthetically derived Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil Hypoallergenic plant fiber is derived from pine cellulose