Lytera 2.0 is a state of the art brightening serum that demonstrated improvement in dark spots and uneven pigmentation as soon as 2 weeks with benefits becoming more dramatic at 12 weeks in clinical studies. It features tranexamic acid, a non-hydroquinone non-retinoid active ingredient that has been garnering global interest as a topical brightener after improvement was noted in patients who received it systemically to stop bleeding due to surgery or trauma. This formula combines it with phytic acid and niacinamide for a synergistic pigment lightening effect, and has the added advantage of incorporating ingredients that are considered to be in pregnancy-safe teratogenicity categories so this is a good option for those looking for a treatment option for melasma or sun spots while pregnant. Lytera was tested with twice-daily full face application and we recommend this for best results, in combination with broad spectrum sun protection, although this can also be applied in combination with other skin brighteners once your skin acclimates to your regimen.