MAPK1/MAPK3 rabbit polyclonal antibody

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Specification Full name MAPK1/MAPK3 rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polycl onal Target Background This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. Swissprot No P28482/P27361 Gene Accession NP_002736/NP_002737 WB Predicted band size 41 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human liver cancer IHC Recommed dilution Recommended dilution: 50-200 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P102161-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or MAPK1/MAPK3 antigen-treated (Neutralization experiment) using P102161(MAPK1/MAPK3 Antibody) at dilution 1/50 Show more