Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.Thorne’s Methyl-Guard Plus features betaine (trimethylglycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.* Benefits of Thorne’s Methyl-Guard Plus: Nutritional support for individuals who have MTHFR gene mutations* Enhanced cellular energy production fights fatigue* Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health* Promotes fat metabolism and lean body composition* Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep* Promotes liver detoxification of many substances, including hormones like estrogen* Why is methylation important:Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in: Cardiovascular health Cellular energy production Fat metabolism Neurological function DNA production Liver detoxification processes Eye health Histamine balance Who can benefit from Thorne's Methyl-Guard Plus: Individuals with mutations to MTHFR and other genes that adversely affect methylation* Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health* Women seeking support for estrogen metabolism and bone health* Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition* Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables Features of Thorne's Methyl-Guard Plus: Betaine, also known as trimethylglycine, is a superior methyl donor The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations* Active forms of vitamins B2 and B6 – key cofactors in methylation processes B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work* Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard® Suggested Use:Take 1-3 capsules daily or as recommended by your health-care practitioner.Warnings:ALLERGY WARNINGThis product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.PREGNANCYIf pregnant, consult your health-care practitioner before using this product.INTERACTIONS5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
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