MethylPro 15mg L-Methylfolate + Cofactors delivers 15mg of pharmaceutical-grade L-5-MTHF combined with targeted methylation cofactors — providing the primary folate support alongside the essential micronutrients that the methylation cycle requires to function optimally. 30 capsules.The cofactor additions go beyond a full B-complex to target the specific upstream and downstream requirements of the methylation cycle: Methylcobalamin B12 (the essential methyl-accepting cobalamin for the methionine synthase reaction), Pyridoxal-5'-Phosphate (P-5-P, for the B6-dependent transsulfuration and aminotransferase reactions), and Zinc (required for methionine synthase and multiple methylation-pathway enzymes). Together 15mg L-5-MTHF + targeted cofactors provides the most comprehensive single-capsule methylation cycle support available. MethylPro is a physician-grade supplement brand from Metabolic Maintenance's L-methylfolate line, providing pharmaceutical-grade L-5-MTHF (as Quatrefolic® or equivalent) — the active, bioavailable form of folate that bypasses the MTHFR conversion step affecting ~40% of the population. Available at Beauty Riche with same-day shipping.