Microbiome Labs Mega IgG2000 is a serum-derived bovine immunoglobulin concentrate (SBI) supplement delivering concentrated IgG, IgA, and IgM immunoglobulins that bind and neutralize pathogenic bacteria, bacterial endotoxins (LPS), viruses, and dietary antigens in the intestinal lumen — providing direct passive immune support in the gut without systemic immunosuppression. 120 capsules.Serum-derived bovine immunoglobulins (from bovine plasma, not colostrum) provide a uniquely broad spectrum of antibody activity against intestinal pathogens and inflammatory antigens. IgG (the primary immunoglobulin) directly binds and neutralizes bacterial toxins, particularly lipopolysaccharide (LPS/endotoxin) from gram-negative bacteria — the primary driver of systemic inflammation, metabolic endotoxemia, and leaky gut-driven inflammatory diseases. By binding LPS in the gut lumen before it can translocate through a compromised barrier, SBI addresses the upstream cause of chronic systemic inflammation associated with metabolic syndrome, autoimmunity, and systemic inflammatory conditions. Clinical studies show significant improvement in intestinal permeability, reduction in inflammation markers, and improvement in GI symptoms. Microbiome Labs is a science-first probiotic and gut health supplement company founded by Dr. Kiran Krishnan, a research microbiologist, built around spore-based probiotic technology and clinical research on the human gut microbiome. Available at Beauty Riche with same-day shipping.