Microbiome Labs ZenBiome Cope is the first probiotic supplement formulated specifically for the gut-brain axis, using the clinically validated psychobiotic strain Lactobacillus rhamnosus JB-1 alongside targeted nutritional support for stress resilience and mood — addressing the bidirectional communication between the gut microbiome and the central nervous system that regulates stress response, mood, and cognitive function.Lactobacillus rhamnosus JB-1 is one of the most studied psychobiotic strains — a specific strain from the Maudsley Institute that in a landmark 2011 Nature Neuroscience study demonstrated: reduction of corticosterone (stress hormone) levels, reduction in anxiety-related behavior, and direct modulation of GABA receptor expression in the brain via the vagus nerve — all absent in vagotomized animals, confirming the gut-brain vagal pathway as the mechanism. Subsequent human studies have confirmed stress resilience benefits. The formula combines JB-1 with complementary nutrients targeting the cortisol response, GABA production, and HPA axis regulation. For patients experiencing chronic stress, anxiety-related gut symptoms, or the gut-brain connection manifestations of mental health. Microbiome Labs is a science-first probiotic and gut health supplement company founded by Dr. Kiran Krishnan, a research microbiologist, built around spore-based probiotic technology and clinical research on the human gut microbiome. Available at Beauty Riche with same-day shipping.
