Microparticle Blocking Buffer. 2 different clones are available. Clone Catalog # 1 L B2010005L 100 mL B2010005S Catalog number: B2010005L B2010005S Lot number: Batch Dependent Expiration date: Batch Dependent Size: 100 mL Storage: 2-8°C Buffer pH 10 Microparticle Blocking Buffer is a biotechnology-grade reagent formulated to minimize non-specific binding and background signal in assays involving microparticles, including latex beads and magnetic particles. Supplied in two clone formats—1 L (Catalog #B2010005L) and 100 mL (Catalog #B2010005S)—this buffer is optimized for use in immunoassays, turbidimetric tests, and particle-based detection systems. With a pH of 10, it provides a stable environment that preserves particle integrity and enhances assay reproducibility. Researchers and assay developers working in diagnostics, inflammation studies, and therapeutic drug monitoring rely on blocking buffers to improve assay sensitivity and reduce cross-reactivity. This buffer supports long-term stability of coated microparticles and is compatible with both manual and automated workflows. Filtered through 0.22 µm membranes and prepared with ultrapure water, it ensures high purity and minimal interference. Stored at 2–8°C, it integrates seamlessly into high-throughput platforms and custom assay formulations. Key benefits: Minimizes non-specific binding in microparticle-based assays Available in 1 L and 100 mL formats for scalable use Optimized pH 10 buffer for particle stability and assay performance Filtered through 0.22 µm membranes using ultrapure water Stored at 2–8°C for long-term reagent stability Products are for in vitro research use only (RUO). References George C, Matsha TE, Korf M, Zemlin AE, Erasmus RT, Kengne AP. The agreement between fasting glucose and markers of chronic glycaemic exposure in individuals with and without chronic kidney disease: a cross-sectional study. BMC Nephrol . 2020 Jan 30;21(1):32. Ghazizadeh H, Rezaei M, Avan A, Fazilati M, Pasdar A, Tavallaie S, Kazemi E, Seyedi SMR, Ferns GA, Azimi-Nezhad M, Ghayour-Mobarhan M. ssociation between serum cell adhesion molecules with hs-CRP, uric acid and VEGF genetic polymorphisms in subjects with metabolic syndrome. Mol Biol Rep . 2020 Feb;47(2):867-875. Moutachakkir M, Lamrani Hanchi A, Baraou A, Boukhira A, Chellak S. Immunoanalytical characteristics of C-reactive protein and high sensitivity C-reactive protein. Ann Biol Clin (Paris) . 2017 Apr 1;75(2):225-229. Veltman EM, Lamers F, Comijs HC, Stek ML, van der Mast RC, Rhebergen D. Inflammatory markers and cortisol parameters across depressive subtypes in an older cohort. J Affect Disord . 2018 Jul;234:54-58. Eto D, Tanaka R, Suzuki Y, Sato Y, Itoh H. Comparison of performance characteristics between high-performance liquid chromatography and latex agglutination turbidimetric immunoassay for therapeutic drug monitoring of zonisamide. J Clin Lab Anal . 2019 Sep;33(7):e22940.
