Millipore Mobius MIX500 Single-Use Mixing and Sampling Assembly – 500 L, Levitating Magnetic Impeller, Needle-Free Sample Ports (MPN: MIX0500L1437887-SP) Expired product - for R&D and process design purposes. The Millipore Mobius MIX0500L1437887-SP is a premium, bioprocess-grade 500 Liter single-use mixing and sterile sampling container assembly engineered for high-security fluid processing in biopharmaceutical manufacturing, vaccine production, and upstream/downstream buffer preparation. Fabricated from multi-layer PureFlex high-durability film, this single-use bag features an integrated, bottom-mounted levitating magnetic impeller that operates without mechanical shafts or bearings to eliminate internal seal friction, particulate shedding, and contamination risk. Optimized for shear-sensitive ingredients, intermediate drug pooling, and media homogenization, this closed system incorporates built-in needle-free sampling valves to enable representative fluid draws without compromising the aseptic process environment. Technical Performance and Design Levitating Magnetic Impeller Technology: Features a bottom-mounted, magnetically coupled impeller that floats during operation. By removing mechanical shafts, bearings, and direct physical contact, this design delivers low-shear mixing while minimizing the risk of bag leaks or particulate contamination. PureFlex Multi-Layer Film Construction: Fabricated from ultra-pure, multi-layer co-extruded PureFlex film. This film structure combines an inert polyethylene fluid contact layer with a high-durability woven nylon strength barrier to deliver exceptional flexibility, high mechanical strength, and an ultra-low extractables profile. Zero Dead-Leg Sterile Sampling: Equipped with specialized needle-free sample ports that interface directly with the mixing container. This design eliminates liquid stagnation zones, ensuring that extracted samples are completely representative of the entire 500 L process volume while protecting against cross-contamination. Closed System Process Efficiency: Eliminates the labor-intensive Clean-in-Place (CIP) and Steam-in-Place (SIP) validation cycles required by traditional stainless steel bioreactors and mixing vats. This single-use design enables rapid multi-product turnaround times and reduces operational downtime. Product Specifications Catalog Number / MPN: MIX0500L1437887-SP (MIX0500L Series) Manufacturer / Brand: MilliporeSigma / Merck KGaA Nominal Processing Volume: 500 Liters (500 L) Assembly Type: Single-Use Mixing and Sampling Liner Bag Film Material Technology: PureFlex Multi-Layer Film (Polyethylene fluid-contact layer) Impeller Configuration: Integrated bottom-mounted magnetic impeller (Polypropylene encasement) Sampling Interface: Integrated needle-free sample valves Sterility / Purity Profile: Gamma irradiated sterile, pyrogen-free, and certified non-cytotoxic for bioprocessing compliance Key Benefits and Applications Biopharmaceutical Media and Buffer Prep: The industry-standard vessel liner for the large-scale homogenization of complex cell culture medias, diagnostic buffers, and intermediate chemical processing reagents. Shear-Sensitive Homogenization: The levitating magnetic drive provides gentle yet highly efficient fluid movement, making it ideal for mixing sensitive protein solutions, monoclonal antibodies, and viral vaccines without structural degradation. Representative Diagnostic Pulls: Built-in sampling channels allow production teams to perform closed-loop pH, conductivity, and purity checks directly from the main batch fluid lines without introducing ambient contamination. Mobile Carrier Compatibility: Engineered to align with standard Mobius MIX500 hardware carriers and automated drive units, ensuring secure outer support, load-cell alignment, and rapid inflation deployment. All product names, logos, and brands are property of their respective owners.
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