MOTS-C

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MOTS-c is a mitochondrial-derived peptide encoded within the 12S rRNA gene of the mitochondrial genome. It is a 16-amino acid peptide that acts as a retrograde signal from mitochon dria to the nuclear genome. MOTS-c is studied as an exercise mimetic that activates AMPK and regulates the folate-methionine cycle in metabolic research models. Show more