mtTFA Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS90890-50, BS90890-100 Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: Q00059(Human) Host: Rabbit Reactivity: Human Applications: WB, ICC/IF, IHC, IP All Applications: WB:1:200-1:500 ICC/IF:1:50-1:200 IHC:1:50-1:200 IP:1:10-1:50 Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M. Purification and Purity: ProA affinity purified Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Specificity: mtTFA polyclonal antibody detects endogenous levels of mtTFA protein. Immunogen: Recombinant protein Conjugate: Unconjugated Modification: Unmodified Note: For research use only, not for use in diagnostic procedure. Extra Notes: Western blot analysis of mtTFA on Hela cell using anti-mtTFA antibody at 1/1,000 dilution., ICC staining mtTFA in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
