Ortho Molecular Natural Vitamin E Mixed Tocopherols Cardiovascular Health Natural Vitamin E Mixed Tocopherols provides full-spectrum, fat-soluble vitamin E to reduce the effects of free radical activity throughout the body. Naturally occurring vitamin E refers to a family of fat-soluble molecules that include tocopherols. There are four different forms of vitamin E tocopherols: alpha, beta, gamma, and delta. The most widely studied forms of vitamin E include alpha tocopherol and gamma tocopherol. Alpha-tocopherol, in its natural d-alpha form, is the form primarily retained in the body and found circulating in the bloodstream. Gamma-tocopherol is the form found most abundantly in food, although heat and oxidation during cooking and processing can destroy it. In the past, most research focused on the role that alpha tocopherol plays; however, new evidence is emerging regarding gamma tocopherol’s role in supporting health. Through its antioxidant activity, vitamin E has been shown to support cardiovascular, neurological, ocular, and immune health. The Natural Vitamin E Mixed Tocopherols formula provides full-spectrum, fat-soluble vitamin E to reduce the effects of free radical activity throughout the body. Natural Vitamin E is formulated to maximize antioxidant protection and provide support for cardiovascular health. The formula includes a blend of mixed tocopherols. Each serving provides 800 IU d-Alpha tocopherol and 400 mg of additional non-alpha tocopherol forms for comprehensive antioxidant protection. Key Benefits and Features: Provides Protection Against Free Radical Damage Maintains Normal Inflammatory Balance Promotes Cardiovascular and Nervous System Health Ingredients Serving Size: 2 Soft Gel Capsules Amount/Serving Vitamin E (from 800 IU as d-Alpha Tocopherol) 536 mg Total non-alpha tocopherol forms 400 mg d-Beta and d-Gamma tocopherols 242 mg d-Delta tocopherols 92 mg Other Ingredients: None. Does Not Contain: Gluten, corn, yeast, artificial colors or flavors. Suggested Use Take 1-2 soft gel capsules per day or as recommended by your health care professional. Warning: If you are pregnant or nursing, consult your physician before taking this product. Keep out of the reach of children. Storage: Keep tightly closed in a cool, dry place. More Info. Antioxidant Support In a study of oxidative stress on human blood cells, mixed tocopherols had a stronger protective effect on lipid peroxidation than alpha-tocopherol alone, due to gamma and delta tocopherols' ability to trap and neutralize other free radicals in the cell. Immune Support and Inflammatory Balance Research has demonstrated that supplementation with vitamin E promotes a healthy immune response. In a study examining vitamin E supplementation in an elderly population, 60 to 800 mg of vitamin E improved several aspects of cell-mediated immunity within six to 12 months. In another study, ingestion of 400 IU of vitamin E for eight months supported immune function by improving macrophage-mediated response. A tocopherol mixture rich in gamma tocopherol has been shown to maintain normal inflammatory balance by reducing oxidative damage, trapping of unique free radicals called reactive nitrogen species, and inhibition of abnormal arachidonic acid metabolism. In animal studies, delta tocopherol was more active compared to alpha or gamma tocopherols in supporting cellular integrity, possibly through trapping reactive oxygen and nitrogen species that cause cellular damage. Cardiovascular Health The oxidation of low-density lipoprotein (LDL) and other lipoproteins can be a major detriment to cardiovascular health. Research has also shown that vitamin E is incorporated into LDLs. By supporting antioxidant activity within LDLs, vitamin E helps maintain cholesterol integrity, normal white blood cell activity, and normal inflammatory balance, which is crucial for cardiovascular health. A double-blinded study found subjects receiving gamma-tocopherol experienced significant cardiovascular support by maintaining healthy LDL cholesterol levels and normal platelet aggregation.
